RU58841 may help some with hair loss, but it can have side effects like heart pain. Dutasteride and finasteride can cause initial shedding, and results may take time.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
A dermatologist recommended using topical Dutasteride (15%) once a week, alongside oral Finasteride and Minoxidil, to improve hair strength and response. The user is seeking experiences or evidence on the effectiveness of this high-concentration regimen.
Mixing Nizoral and T-Gel in a 1:1 ratio and using it three times a week provided relief from persistent seborrheic dermatitis. This treatment is recommended for those with stubborn SD.
The post discusses a user's hair loss treatment journey over a year, using finasteride, dutasteride (dut), and oral minoxidil (min). The user found finasteride ineffective, switched to dutasteride and oral minoxidil, and noticed improvements, but couldn't determine which of the latter two treatments was most effective.
A user, 18, is considering switching from topical finasteride (0.025%) and minoxidil to dutasteride due to continued hair shedding. Other users shared their experiences with dutasteride, noting potential benefits and risks, including reduced sperm count.
A 36-year-old switched from Finasteride to Dutasteride after 6 years due to thinning hair, adding oral Minoxidil for regrowth. Dutasteride improved hair thickness with fewer side effects, while Finasteride caused anxiety and back pain.
The user switched from finasteride to dutasteride in January and noticed increased crown thinning, despite using minoxidil with rosemary, biotin, and castor oil. They are concerned about hair loss and considering visiting a clinic for further advice.
The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.
A user received brand name Avodart instead of generic dutasteride for a lower price. Another user mentioned experiencing depression as a side effect but prefers having hair.
A 25-year-old is experiencing hair thinning despite using 0.5mg oral dutasteride, 0.3% topical finasteride, and 6% topical minoxidil daily for a year. They are considering increasing dutasteride dosage and exploring other treatments like microneedling and KX 826, while seeking further medical opinions on their condition.
The user is considering a hair loss treatment plan involving oral dutasteride (2.5 mg), oral minoxidil (2.5-10 mg), topical finasteride, and topical minoxidil, with additional options like ketoconazole shampoo and microneedling. They are seeking advice on whether to start with finasteride or dutasteride, the potential side effects, and the effectiveness of their approach, with a plan to evaluate results after 3-4 months.
User shared their 14-month progress using topical Dutasteride at 0.1% for hair loss, with significant improvement and no side effects. Others discussed concerns about fertility and questioned the authenticity of the results.
The conversation is about seeking recommendations for clinics in Los Angeles that offer dutasteride mesotherapy for hair loss treatment. The user is asking for experiences and suggestions from the community.
A user is planning to use mesotherapy with 0.025% dutasteride for hair maintenance due to intolerance to finasteride. They seek clinics in Northern Germany, Sweden, or nearby countries for dutasteride scalp injections.
Monthly microneedling combined with low-dose topical dutasteride shows promising results for hair density and thickness with minimal side effects, especially in the frontal area. Despite its effectiveness, it is not widely discussed or used due to availability and cost concerns.
The user switched from Finasteride to topical Dutasteride, Pyrilutamide, and Minoxidil due to hair loss, then decided to switch to oral Dutasteride because of pregnancy concerns. They are considering the frequency of oral Dutasteride use, with suggestions of using it a few times a week for better results and fewer side effects.
The user started using Dutasteride and topical Minoxidil about six months ago. Opinions vary, but some users notice healthier hair, while others see no significant regrowth.
First patient dosed with Pyrilutamide (Kintor) Phase III for hair loss treatment. Pyrilutamide differs from approved treatments as it competes with DHT to bind hair follicles, potentially reducing side effects.
The user has been using oral finasteride and minoxidil for 1.5 years with some crown improvement but still experiences thin hair and a receding hairline. They are considering switching to dutasteride for potentially better results, while others suggest adding topical minoxidil back into the routine.
Combining finasteride and dutasteride may enhance hair regrowth by targeting different enzymes, with positive results reported. Minoxidil, both oral and topical, is also used to improve effectiveness.
A woman experienced hair regrowth after using self-prescribed finasteride and dutasteride from online sources, despite doctors' reluctance to prescribe these due to potential birth defects. Her dermatologist acknowledged the effectiveness of these treatments and advised her to continue using them while avoiding pregnancy.
A 26-year-old male is documenting his hair regrowth journey using 0.5mg dutasteride and 5mg oral minoxidil, transitioning from 5% topical minoxidil. He reports no significant side effects after one week, except for slight water retention and increased libido.
Kintor Pharma finished enrolling and dosing participants in a Phase I trial for a hair loss treatment called AR-PROTAC (GT20029). The effectiveness of another drug, pyrilutamide (KX-826), for hair loss will be clearer after a Phase 2 trial expected to complete in January 2023.
Switching from finasteride to dutasteride led to hair loss despite continued use of minoxidil. Many recommend reintroducing finasteride, as responses to treatments can vary.
A 5 year journey of using Dutasteride and Minoxidil for hair loss, with progress pictures shared by the user. Replies have expressed amazement at the progress.
The post discusses a user's hair loss treatment involving Dutasteride 2.5 mg 5 times per week, Finasteride 1mg 4 times per week, RU58841 daily, and Minoxidil twice daily. A reply suggests that the combination is excessive, particularly the use of both Dutasteride and Finasteride, and labels it as a "chemical castration protocol".
The post discusses a user's hair regrowth journey from September 2020 to June 2023, using treatments like Finasteride, Dutasteride, and 5% Minoxidil. The user shares progress pictures, discusses the effects of the treatments, and answers questions about his routine and experiences.
A dermatologist advised stopping dutasteride after six months and switching from whey to pea protein, but users disagreed, citing no evidence linking whey to hair loss. The original poster plans to continue dutasteride for six months and switch to pea protein for peace of mind.