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      community Tretinoin Gel + Minox procedure or tips for a minox low responder

      in Treatment  8 upvotes 2 years ago
      A user has been using minoxidil without noticing improvements and is considering adding tretinoin gel to their regimen before trying RU58841. They seek advice on how to mix and apply tretinoin with minoxidil, including concentration and application frequency.

      community Sooo whats the consensus about pp405 now?

      in Chat  74 upvotes 2 weeks ago
      PP405 may help with hair regrowth, especially when combined with minoxidil and finasteride, but its long-term effectiveness is unclear. Phase 3 trials are expected to begin soon, with results in a few years.

      community Applying Tertinoin + Moisturiser on scalp.

      in Chat  1 upvotes 1 year ago
      A user is treating hair loss with oral finasteride, topical minoxidil, and tretinoin mixed with moisturizer for easier scalp application. They also plan to use a derma pen weekly.

      community The use of peptides to enhance hair growth from wounding

       4 upvotes 8 years ago
      The conversation discusses using peptides BPC-157 and TB-500, combined with microneedling, to potentially enhance hair regrowth. The user plans to try BPC-157 due to its lower cost and reports of hair growth, despite limited human trials and concerns about side effects from other treatments like minoxidil and finasteride.

      community Am I missing something with pp405?

      in Research/Science  32 upvotes 1 year ago
      PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

      community TresslessGPT is available to ChatGPT Plus users

      in πŸ“£ Announcement  107 upvotes 2 years ago
      The conversation introduces a specialized chatbot for ChatGPT Plus users that provides advice on hair loss treatments, drawing from research and community insights. It mentions treatments like RU58841, the "big 4" (likely minoxidil, finasteride, ketoconazole, and tretinoin), dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community Pp405 - lowkey kinda bad results

      in Treatment  16 upvotes 9 months ago
      PP405 increased hair density by 20% in 31% of participants, but results are considered underwhelming. Minoxidil and finasteride are seen as more effective treatments.

      community What is the deal with "longitudinal partial follicular unit transplantation"

      in Transplants  4 upvotes 6 years ago
      Longitudinal partial follicular unit transplantation involves extracting part of the donor follicular unit, allowing the donor area to be overharvested without noticeable hair loss. The conversation questions if this method is practiced in clinics or if it's theoretical, and whether it relates to hair cloning or multiplication.

      community Anagenic Pyrilutamid, has anyone tried this?

      in Product  2 upvotes 2 years ago
      The conversation is about personal experiences with Anagenic Pyrilutamid for hair loss and what carriers people use with it. No specific treatments or outcomes are mentioned.

      community VDPHL01 works really quickly .. apparently?

      in Research/Science  49 upvotes 2 weeks ago
      VDPHL01 shows faster and stronger hair growth compared to standard minoxidil, with no major side effects reported. Users discuss combining it with other treatments like dutasteride and finasteride for better results, while expressing skepticism about the effectiveness of PP405.

      community Are we underestimating systemic absorption with homemade/generic Topical Fin? (HPCH vs. PG/Ethanol formulations)

      in Research/Science  4 upvotes 2 months ago
      Topical finasteride may have higher systemic absorption and lower efficacy when using a Propylene Glycol/Ethanol formulation compared to the hydroxypropyl chitosan (HPCH) formulation. The safety profile of topical finasteride relies heavily on the HPCH formulation, and using standard solutions might lead to different pharmacokinetics.

      community Another transplant or SMP? (Not balding)

      in Transplants  23 upvotes 2 months ago
      The user is considering another hair transplant or scalp micropigmentation (SMP) for a congenital bald spot, but previous transplants were less effective due to scar tissue. Suggestions include using hair fibers, changing hairstyles, or doing nothing, as the spot is not very noticeable.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 1 month ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.

      in Research/Science  218 upvotes 9 months ago
      PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.

      community Any results with black market pp405

      in Is this regrowth?  11 upvotes 8 months ago
      PP405 is being discussed for hair regrowth, with mixed opinions on its effectiveness and legitimacy. Some users report early signs of regrowth, while others are skeptical about its authenticity and results.

      community Verteporfin test long term results

      in Treatment  16 upvotes 3 years ago
      Testing the effectiveness of Verteporfin as a potential treatment for hair loss, with users discussing their thoughts on its long-term results. Treatments mentioned include Minoxidil, Finasteride, and RU58841.

      community Natural methods of reversing MPB

       5 upvotes 6 years ago
      The conversation discusses natural methods for addressing male pattern baldness, with the original poster using a plant-based diet, herbs, scalp massages, pumpkin seed oil, and dermapen treatments, while avoiding pharmaceuticals like minoxidil and finasteride due to concerns about side effects. Other users suggest that pharmaceuticals like finasteride may be necessary for significant hair loss, but the original poster remains committed to natural approaches.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  50 upvotes 1 year ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community formula 82D for diffuse androgenic alopecia (DUPA)

      in Is this regrowth?  17 upvotes 1 year ago
      The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

      community Thoughts on platelet-rich plasma therapy

      in Treatment  3 upvotes 1 year ago
      Platelet-rich plasma (PRP) therapy for hair loss is expensive, painful, and often ineffective, with mixed reviews on its benefits. Alternatives like minoxidil, finasteride, and hair transplants are suggested as more reliable options.