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      community Kintor starts a new Phase 3 for Pyri... (1+ year)

      in Research/Science  16 upvotes 3 years ago
      The conversation discusses Kintor's initiation of a new Phase 3 trial to assess the long-term safety of Pyrilutamide (KX-826) for hair loss, which will last 52 weeks. Specific treatments mentioned include Pyrilutamide.

      community pyrilutamide solution progress log

      in Product  20 upvotes 3 years ago
      A 28 year old using a hair loss prevention protocol to restore thinning hair, which includes finasteride, dutasteride, minoxidil, stemoxydine, alopecin, nizoral shampoo and microneedling; the user is now adding pyrilutamide solution to the regimen with the hope of improving their results. RU58841 was also ordered but not yet used.

      community Highest DHT level you’ve seen?

      in Update  6 upvotes 3 months ago
      The conversation discusses starting finasteride 1mg daily for hair loss and mentions a high baseline DHT level. Users comment on the unusually high DHT level and its potential causes.

      community Exit strategy advice: 2nd transplant vs. electrolysis to soften hairline

      in General  99 upvotes 9 months ago
      A 32-year-old male is considering options to soften a dense transplanted hairline after experiencing accelerated hair loss and intolerance to finasteride and dutasteride, while using minoxidil. He is exploring partial electrolysis or laser treatments to achieve a natural look with a short buzz cut, avoiding a second transplant or scalp micropigmentation.

      community Personal experiment: tretinoin and diffuse thinning

      in Treatment  9 upvotes 3 years ago
      User experienced hair growth with finasteride and minoxidil, but after using tretinoin, faced aggressive thinning and hair loss. They plan to stop tretinoin for two months to see if the problem improves.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  10 upvotes 2 years ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community Tressless When They See Verteporfin Results

      in Transplants  181 upvotes 2 years ago
      The conversation discusses the potential of Verteporfin, an FDA-approved drug, for hair loss treatment, particularly in combination with microneedling or PRP. Users express hope and curiosity about its application, while some remain cautious due to the need for more extensive testing.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community Update progress on Fin, Min, and Kx-826

      in Is this regrowth?  7 upvotes 1 year ago
      The user is using oral finasteride, minoxidil, and KX-826 for hair regrowth, noticing small improvements. They plan to add ketoconazole shampoo and consider a hair transplant with verteporfin after a year of treatment.

      community What’s in Your 'Dream' Topical?

      in Treatment  6 upvotes 1 year ago
      The conversation discusses creating a personalized topical treatment for hair loss, with ingredients like finasteride, minoxidil, tretinoin, melatonin, caffeine, and others. Users share their ideal formulations, including combinations of minoxidil, finasteride, tretinoin, adenosine, and other compounds, while also discussing the importance of managing inflammation.

      community Switching to a more aggressive stack

      in Progress Pictures  4 upvotes 4 months ago
      The conversation is about a user switching to a more aggressive hair loss treatment, adding dutasteride 0.5mg and oral minoxidil 2.5mg to their current regimen of finasteride 0.02%, minoxidil 5%, biotin, massages, and microneedling. Users suggest increasing finasteride dosage and caution about potential side effects of oral minoxidil.

      community Stem-cell hair transplants! 20k lab grown grafts from one single graft

      in Chat  46 upvotes 2 years ago
      Stem-cell hair transplants could potentially create thousands of grafts from a single donor graft, offering a solution for hair loss with DHT-resistant hair. Companies like Stemson Therapeutics and OrganTech are working on this technology, which may become available in the future, possibly reducing the cost and making it widely accessible.

      community topical exosomes - experimenting

      in Treatment  1 upvotes 4 months ago
      The conversation is about experimenting with topical exosomes for hair loss treatment, alongside microneedling, Happy Head's gel-like topical, and Ordinary's hair serum. The user also mentions the availability of treatments like latanoprost and Redensyl.

      community Does anybody else got their hair ruined when on tretinoin?

      in Chat  4 upvotes 2 years ago
      The user experienced hair shedding and follicle shrinkage when using retinoic acid, despite trying different concentrations and frequencies. The hair loss persisted for six months but regrew after stopping the treatment.

      community (MTF 35) Results of 18 Months of HRT

      in Transgender  783 upvotes 7 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community Are there alternatives to finasteride?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about seeking alternatives to finasteride for hair loss treatment due to concerns about sexual side effects, with pyrilutamide mentioned as a potential alternative.

      community Most Recent Interesting Hairloss Studies: 10% Minox vs 5% Minox / Radio Rrequency Treatment for AA / Topical Ketoconazole / PRP+Minox vs Minox vs PRP / Alopecia as a systemic disease

      in Treatment  87 upvotes 6 years ago
      Treatments for hair loss, such as topical minoxidil, platelet-rich plasma therapy with or without minoxidil, ketoconazole, non-abative radio frequency, natural products, finasteride and cortexolone 17 alpha propionate. The post evaluates the efficacy and safety of these treatments in various studies.