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330-360 / 1000+ resultscommunity EMA is re-examining Winlevi (clascoterone at lower concentration)
Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.
community Can mixing RU with min compounded with tretinoin cause the RU to go sytemic
Mixing RU58841 with minoxidil compounded with tretinoin is discussed, with concerns about systemic absorption. Topical dutasteride and finasteride are also mentioned as treatments, with varying personal experiences and concerns about side effects.
community Progress finally (?) 4 months left & right temple
The user has been using finasteride for two years without results and recently started a new routine involving derma stamping, retinol, and minoxidil, which seems to show progress. The user microneedles about half the week and uses L’Oréal night serum for retinol.
community Added Tretinoin to my my routine and am shedding like crazy.
The user has been using finasteride and minoxidil for almost 2 years with maintenance but no significant regrowth. After adding tretinoin 2 weeks ago, they experienced increased shedding and are seeking advice on whether this is a positive sign.
community Can't help but feel somethings wrong (MtF 18)
The user is experiencing hair loss and is using treatments like finasteride, minoxidil, and hormone replacement therapy (estradiol enanthate injections) to address it. They are advised to be patient with the treatments and consider using a dermapen for microneedling.
community RU58841 vehicle penetration (Study for minoxidil)
The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.
community Finally seeing some good regrowth after 7 months on treatment
The conversation discusses hair regrowth after 7 months of treatment, with the recent addition of tretinoin 0.05%. The treatment routine remained the same as before, except for this new addition.
community People that had night and day difference from just Fin/Dut+Min to Fin/Dut+Min+Tret, what prompted you to add Tretinoin?
Adding tretinoin can enhance the effectiveness of minoxidil by increasing sulfotransferase levels, making it beneficial for hair growth. However, it may not be necessary if using oral minoxidil.
community Verteporfin Update #2: Day 1 through Month 1 | Dr Blake Bloxham | Feller & Bloxham Medical | NY, NYC
The conversation discusses the use of Verteporfin in hair loss treatment. It suggests that Verteporfin could potentially regenerate hair follicles instead of forming scars, providing an unlimited donor supply for hair transplants.
community topicals after microneedling cause burning sensation
Microneedling followed by applying green tea caused a burning sensation on the scalp. The user is seeking advice on whether this reaction is normal.
community 7.5 Months on Min + Fin — Progress Pics + Questions (Crown, Temples, Folliculitis)
The user has been using minoxidil and finasteride for 7.5 months to address hair thinning, particularly at the crown and temples, and is considering additional treatments like tretinoin and dermastamping despite having chronic scalp folliculitis. They are experiencing progress but are concerned about side effects and the effectiveness of treatments on temple regrowth.
community Derminator2 causing scars (microscope images attached)
User experienced scarring from microneedling at fast speed and paused treatment for 3-4 weeks to recover. Advice given includes waiting a full month for recovery to avoid scars.
community Extreme shedding after ~1 year on 5% topical minoxidil — normal or problem?
A 17-year-old using 5% topical minoxidil experienced significant hair shedding after a year, possibly due to a "synchronization shed" and deficiencies in vitamin D and iron. Recommendations include continuing minoxidil, optimizing vitamin D and iron levels, and reducing tretinoin use if scalp irritation occurs.
community is there anything that stops hair loss?
A user is experiencing rapid hair loss and has been diagnosed with telogen effluvium by multiple dermatologists, but doubts the diagnosis due to the severity and speed of the hair loss. They are considering various treatments like spironolactone, estradiol, and possibly finasteride, while also exploring the possibility of hormonal imbalances or autoimmune issues.
community Redensyl Megathread !!!!
Redensyl, which is a topical alternative to Minoxidil for hair loss. It may have advantages such as not making the hair greasy and lasting longer after discontinuing use than minoxidil. There are some positive reports from users, but also some negative ones, so it's unclear how effective this treatment will be in comparison to Minoxidil and other treatments like Finasteride or RU58841.
community Why does hairloss look great one day and regression the next?
Hair appearance fluctuates due to factors like styling, product buildup, and humidity, causing frustration for those with diffuse thinning. Treatments mentioned include minoxidil, finasteride, ketoconazole shampoo, and RU58841, with mixed results.
community results: 15 months fin + 4.5 months estrogen monotherapy + 4.5 months min
The user has been using finasteride for 15 months, minoxidil for 4.5 months, and estrogen monotherapy for 4.5 months. Their current regimen includes finasteride, minoxidil, alfatradiol, and estradiol gel.
community How quick does topical fin absorb?
Topical finasteride absorption starts almost instantly, but the exact time needed for full absorption is unclear. Users suggest it may not need to stay on all day.
community Verteporfin trials in hair transplant patients begin
A clinical trial for Verteporfin as a hair loss treatment, and the potential for greater progress in treatments for hair loss in the future. Common treatments such as Minoxidil, Finasteride and RU58841 were discussed.
community Atypical hair loss, weird response to finasteride
community 1.5 years topical minox 0.5 ml twice (just temples) + 0.5 mg oral finasteride daily.
The user experienced hair regrowth and improved hair quality using topical minoxidil on temples and oral finasteride daily. They also noted thicker eyebrows and some side effects like minor erectile dysfunction.
community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)
The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.
community Verteporfin day 84 update - donor hair regeneration human trials
A human trial involving verteporfin for hair regeneration, with the results showing some regrowth of 1-2 hairs in an area where a follicular unit was extracted. The conversation also suggested that future studies should involve higher doses and more frequent injections.
community Topical Melatonin for mild aga
The conversation is about an 18-year-old male considering topical finasteride for hair loss and asking about the effectiveness of topical melatonin for hair regrowth and density. No specific treatments were confirmed to be used.
community Ru delivery and heat outside .
The conversation discusses concerns about the effectiveness of RU58841 due to high temperatures during delivery. A user reassures that the heat will not affect its efficacy.
community How well can HRT reduce scalp tension?
A trans woman is curious about the impact of HRT on hair regrowth and scalp tension. Her current regimen includes finasteride, spironolactone, estradiol, ketoconazole, vitamin D, iron, and plans to add oral minoxidil and restart derma rolling.
community Verteporfin day 119 update - donor hair regeneration human trial
A human trial involving the use of Verteporfin as a treatment for hair loss, which has been ongoing for 119 days with an update on its progress. Treatments such as Minoxidil, Finasteride and RU58841 have also been discussed.
community Tretinoin and Minoxidil Works!
community Alfatradiol causing shedding ?
The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.