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GlossaryTrichothiodystrophy

rare genetic disorder causing brittle hair and developmental issues

Trichothiodystrophy (TTD) is a rare genetic disorder characterized by brittle hair due to a deficiency in sulfur-containing proteins. It often involves other symptoms such as intellectual disability, developmental delays, and photosensitivity. The condition is linked to mutations in genes involved in DNA repair and transcription, making it a complex syndrome with a wide range of clinical manifestations.

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community Is trichogram a good thing for testing genetic hair loss

in Research/Science 2 upvotes 3 months ago

A dermatologist checked for hereditary hair loss using blood tests and plans to perform a trichogram. The user had slightly low Vitamin D3 levels, and the trichogram may help confirm androgenetic alopecia.

community Trichotest results in… min not on my list! Just Fin/Dut, Zinc… and the insanely expensive latanoprost & prostaquinon.

in Technology 22 upvotes 4 years ago

Hair loss discussion includes treatments like hinoki tree oil and procyanidin b2. Experiences and effectiveness of these treatments are shared.

community trichoscopy: for those of you with microscopes

in Research/Science 7 upvotes 1 year ago

The conversation discusses using USB microscopes for scalp photos and provides a link to an overview of trichoscopy. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community 21m, curious about what's going on with my hair

6 upvotes 11 years ago

A 21-year-old male with a thyroid condition noticed his hair thinning uniformly without a receding hairline. He is considering using a 5ARI to prevent further baldness if he starts TRT.

community Naturally high T (1,100+) causing diffuse thinning while on Dut

in Chat 22 upvotes 2 months ago

A 26-year-old male with high testosterone is experiencing diffuse hair thinning despite using a comprehensive treatment regimen including dutasteride, oral minoxidil, RU58841, ketoconazole shampoo, microneedling, and low-level laser therapy. Suggestions include adjusting dutasteride dosage, monitoring iron levels, and consulting a dermatologist for further evaluation.

community Losing hair without the white bulb, Tressless GPT's Response. Do you guys agree?

in Treatment 4 upvotes 1 year ago

Hair loss without a white bulb may indicate mechanical damage, anagen effluvium, alopecia areata, or traction alopecia. Seeking a specialist is recommended, but access can be difficult in smaller areas.

community 17M with Diffuse Thinning, Dandruff, and Body Hair Shedding

in Basic Questions 93 upvotes 4 weeks ago

A 17-year-old is experiencing diffuse thinning, dandruff, body hair shedding, and other symptoms, possibly linked to seborrheic dermatitis or telogen effluvium. They are using ketoconazole shampoo and considering blood tests to check for thyroid issues or deficiencies.

community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

in Research/Science 63 upvotes 2 years ago

Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

community 19, Trichologist Avoiding Minoxidil, Slow Progress with Seborrheic Dermatitis Treatment

in General 77 upvotes 3 months ago

The trichologist avoids recommending Minoxidil, focusing instead on changing medications monthly for seborrheic dermatitis, resulting in only slight improvement in hair quality and loss. The user is considering starting Minoxidil independently due to slow progress and personal distress.

community My skin is always dry and flakes like chalk (25)

in Transgender 6 upvotes 2 years ago

The user underwent a biopsy two years ago and was diagnosed with keratosis pilaris, leading to hair issues. They tried treatments including Minoxidil, betamethasone, lymecycline, topical Accutane, and dutasteride, as well as diet changes, without improvement in hair thickness or skin dryness.

community can someone help me identify these pls

in Treatment 6 months ago

The user is experiencing diffuse thinning and inflammation despite using 2.5mg dutasteride daily, ciclopirox, and ketoconazole shampoos. They are considering treatments like hydroxychloroquine and JAK inhibitors due to suspected scarring alopecia and have faced challenges in obtaining a scalp biopsy.

community Can trichodynia ruin an exosome treatment?

in Chat 1 upvotes 1 year ago

The user has tried various hair loss treatments including topical minoxidil, oral finasteride, oral dutasteride, oral minoxidil, and exosome therapy, but none have been effective. They suspect trichodynia might be preventing these treatments from working.

community [Discussion] Trichoscopy in sudden-onset AGA: Pathology and reversibility of "Yellow Dots" without 5AR-inhibitors?

in Research/Science 5 upvotes 2 months ago

Hair loss treatments discussed include microneedling, minoxidil, tretinoin, finasteride, dutasteride, pumpkin seeds, saw palmetto, and scalp massage. The consensus is that finasteride or dutasteride is necessary for significant regrowth, while other methods may only slow hair loss.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 3 years ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community My experience with Trichogenics

in Progress Pictures 6 upvotes 2 years ago

A user shared their positive experience with Trichogenics for hair restoration, highlighting their unique zigzag hairline technique and personalized attention. They had 1700 follicles transplanted and praised the natural results.

community Predicting Your Hair Loss with a Trichoscopy Report

in Treatment 7 upvotes 2 years ago

The conversation discusses the use of trichoscopy to predict hair loss patterns and inform treatment approaches. Treatments mentioned include minoxidil, finasteride, and dutasteride, with varying effectiveness based on gender-specific hair loss patterns.

community Non responsive diffuse thinning

in Progress Pictures 9 upvotes 8 months ago

The user has been experiencing diffuse hair thinning despite using finasteride, minoxidil, dermarolling, clobetasol cream, and PRP sessions. They seek advice on additional treatments and are advised to check vitamin D, iron, and thyroid levels.

community mallia therapeutics 8T3 scd83 molecule for ffa/lpp mainly and aga

in Technology 9 upvotes 4 months ago

A user applied the 8T3 product for hair loss, targeting LPP and AGA, and plans to update on its effectiveness. The product uses a saline buffered phosphate vehicle, suitable for those intolerant to ethanolic vehicles.

community "DHT Itch" and onset Seborrheic Dermatitis

in Research/Science 76 upvotes 2 years ago

The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

community DHT levels and correlation to hair loss

in Chat 3 upvotes 8 months ago

The user experienced hair shedding after starting testosterone replacement therapy (TRT) and is considering using DHT blockers like finasteride or dutasteride to address potential DHT-related hair loss. Low ferritin levels due to frequent blood donations may also contribute to hair issues, and the user is working on stabilizing iron levels.

community DUPA / APHK discussion ( Diffuse unpatterned alopecia / Acquired Progressive Hair Kinkering )

in Treatment 4 upvotes 6 years ago

The user discusses their experience with diffuse unpatterned alopecia and acquired progressive hair kinkering, noting improvements with treatments including biotin, pantothenic acid, finasteride, ketoconazole, and zinc pyrithione shampoo. They report thicker, healthier hair and improved scalp condition, attributing success mainly to biotin, pantothenic acid, and finasteride.

community Using trichosol as a vehicle for finasteride, minoxidil etc.

in Treatment 4 upvotes 3 years ago

User discusses using trichosol as a vehicle for hair loss treatments like finasteride and minoxidil. They ask about others' experiences and the stability of the solutions.

community A hill on which I will die: The DHT itch absolutely exists

in Research/Science 210 upvotes 2 years ago

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

community Vitamin E and K deficiency (F,25)

in Research/Science 3 upvotes 1 month ago

Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.

community hello

144 upvotes 7 years ago

A 12-year-old diagnosed with alopecia shares their experience and current treatments, including Dermovate, an unnamed cream, and liquid iron. The community offers support and encouragement.

community Sudden Triangular Thinning Patch

in General 157 upvotes 9 months ago

A 31-year-old has been using finasteride, dutasteride, and oral minoxidil for hair loss. They noticed a sudden triangular thinning patch on their scalp and are seeking advice, questioning if it could be medication-related.

community Dont know what the hell is going on.

in Chat 6 upvotes 1 year ago

The user experienced rapid diffuse hair thinning for five years despite no signs of AGA or miniaturization. They tried finasteride and oral minoxidil without success and have checked thyroid, iron, and vitamin D levels.

community Sweet Lord my DHT itch is finally gone

in Chat 49 upvotes 3 years ago

Hair loss itch stopped by adding RU58841 to treatment. Topical Finasteride and Pyrilutamide also mentioned as potential itch solutions.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 3 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community Trichoscopy. 5 month difference. Picture of my sink after applying sea salt spray

in Minoxidil 5 upvotes 1 year ago

The user is using minoxidil and finasteride to treat hair loss and is concerned about shedding and potential aggressive hair loss. They noticed some regrowth in trichoscopy pictures but are unsure about real-life changes.