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600-630 / 1000+ resultscommunity Koshine 826 (Pyrilutamide). Any results after 5 months since it's been released?
Koshine 826 (Pyrilutamide) has mixed reviews, with some users experiencing side effects like insomnia and others seeing minimal results. Concerns about the company's transparency and lack of progress photos are noted.
community 8 months of oral dut-min and keto shampoo, thanks r/tressless!
A user shared their progress after 8 months of using oral dutasteride, minoxidil, and ketoconazole shampoo for hair loss. They are very pleased with the results.
community Has anyone tried this brand for ru?
The conversation is about a user experiencing hair shedding after using a brand of RU58841, questioning its effectiveness and safety. Concerns are raised about RU58841 being an abandoned research chemical and the use of heavy oils like castor and argan oil potentially affecting absorption.
community 13 months Progress on Dut + Minox. I am happy.
The conversation is about someone's 13-month hair regrowth progress using 0.5 mg Dutasteride daily, 5% Minoxidil twice daily, Biotin tablets, and Sebizole shampoo. They are happy with the results.
community Today I start with this: RU58841
The conversation is about a person starting treatment with RU58841 for hair loss. They are asked to share progress pictures to show if the treatment is effective.
community RU question - personal experiences + what dose are you guys doing?
RU58841 has significantly improved the user's hair loss experience, alongside oral finasteride, dutasteride, 5 mg minoxidil, topical finasteride, dermastamping, and low-level laser therapy. The user is considering increasing their RU58841 dose from 75 mg to 100-150 mg daily.
community Thank You Tressless, A Tale Of A Hyper Responder
A user shared their successful hair regrowth journey using finasteride, oral minoxidil, and oral dutasteride, expressing gratitude for the support received. The conversation includes congratulations and encouragement from others.
community Tretinoin can enhance the skin permeability of Minoxidil approximately 3-fold at 0.05%[24] and itself has some hair regrowth properties.
The conversation discusses enhancing Minoxidil absorption for hair loss treatment using Tretinoin and MSM (Methylsulfonylmethane). The user is seeking sources for Tretinoin and mentions MSM's potential to improve the absorption of topical agents.
community (26M) I just received the test results for my hair loss.
A 26-year-old man with diffuse alopecia is using electric scalp massage, dermastamp, and multivitamins for treatment but is intolerant to finasteride. A dermatologist recommended PRP and mesotherapy with exosomes and dutasteride.
community Kintor Pharma Announces Completion of First Patient Enrollment in KX-826 Long-term Safety Phase III Trial for Treatment of AGA
Kintor Pharma has finished enrolling the first patient in a Phase III trial for KX-826, a treatment for androgenetic alopecia (AGA). One user has set a reminder to check back on the topic in a year.
community How do you apply Tretinoin for Minoxidil extra results? (Apparently makes non responders respond)
People are discussing using tretinoin gel with minoxidil to improve hair growth, especially for those who didn't respond to minoxidil alone. They apply a mix of tretinoin gel and minoxidil to the scalp, which is said to be more effective than minoxidil by itself.
community Protac degradation of the androgen receptor in mice shows good efficacy and no systemic drug could be found
The efficacy of degrading the androgen receptor through dermal application in DP cells, a delivery system for topical drugs that involves dissolving microneedles, and rosemary oil as an alternative anti-androgen.
community 40 days progress with DUT, microneedling, and minoxidil.
The progress of one user's hair loss treatment regimen involving Dutasteride, microneedling and minoxidil, with positive results seen after 40 days. Replies offered encouragement and advice for continued progress over the next year.
community 4.5 Months Dut + Tretinoin/Topical Minoxidil Combo 50 Days vs. Oral Minoxidil 100 Days
The user experienced significant hair regrowth on temples and beard using a combination of Dutasteride, Tretinoin, and topical Minoxidil, but stopped oral Minoxidil due to heart pain. The user switched from Finasteride to Dutasteride due to aggressive hair loss.
community Expectations control for SCUBE3
SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.
community ICYMI: Eirion ET-02’s Successful Phase 1 Trial Results for Androgenic Alopecia Treatment
ET-02 showed significant hair growth in five weeks, outperforming minoxidil, with a non-hormonal mechanism that avoids side effects of treatments like finasteride. A phase 2 trial is planned to further assess ET-02's efficacy and safety.
community Woolly mice but no hair growth treatment for humans yet 🤷♂️
Hair regrowth treatments are effective in mice but not yet available for humans. The discussion humorously highlights frustration over this disparity and mentions a project to genetically modify elephants to resemble mammoths.
community 3 months on topical fin/min/stamping
The user has been using a topical combination of finasteride, minoxidil, and dermastamping for three months to address hair loss. They are considering adding tretinoin and are discussing the effectiveness of topical versus oral treatments.
community Pyrilutamide phase III clinical trial results released
Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.
community Links tressless
The conversation is about hair loss treatments, including dermarolling, Minoxidil, Finasteride, and RU58841. Users discuss their experiences, side effects, and application methods for these treatments.
community is RU worth it if you already take dut and min?
A user taking dutasteride and minoxidil for hair loss is considering adding RU58841 to their regimen due to unsatisfactory results. Other users suggest alternatives and discuss the potential temporary benefits and limitations of RU58841.
community Topical Solution Mix: Stemoxydine, RU-58841, Alfatradiol, and Tretinoin - Feasibility and Potential Interactions?
A user is considering mixing Stemoxydine, RU-58841, Alfatradiol, and Tretinoin into a single topical solution for hair loss. They are concerned about potential interactions that could reduce the effectiveness of these ingredients.
community How's your progress on kx-826 (pyrilutamide)?
People are discussing their experiences with kx-826 (pyrilutamide) for hair loss, using concentrations of 0.5% and 0.9%. They are sharing personal results and progress with this treatment.
community Pryri journey update 2 weeks so far.
A 2-week journey with Pyri, which is producing positive effects on hair texture and reduced shedding; Minoxidil and derma needling are being used as treatments.
community 6 month post-transplant, Dr Carman MD surgeon
A user shared their positive experience with a hair transplant performed by Dr. Timothy Carman, using 1100 grafts via FUT surgery, and reported satisfaction with the results and minimal scarring. The user continues to use minoxidil and finasteride for hair maintenance.
community 3 months update on meds post HT
The user started using 1mg finasteride and Regaine foam post-hair transplant, noticing significant hair growth at three months. They experienced testicular cramps as a side effect but no other issues, and are considering microneedling for further improvement.
community topical minoxidil (5%) & kx826 (.5%) update.
The user has been using topical minoxidil (5%) for two years and kx826/pyrilutamide for one year, after experiencing side effects from finasteride. They report positive results from the combination of minoxidil and kx826 in combating hair loss.
community How would you react if PP405 isn't successful in phase 3 trials?
People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.
community Very high free testosterone on dut…
The user has high free testosterone and is still experiencing hair loss despite taking dutasteride and oral minoxidil for over three years. They are considering adding a topical anti-androgen like RU58841.