Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
A 24-year-old reported new hair growth on temples after 3.5 months of using topical minoxidil without shedding. They plan to add finasteride to maintain progress, as minoxidil alone may not be enough long-term.
A user had a positive experience with affordable FUE hair transplants at Harmony Clinic in Cancun, Mexico, noting professionalism and good results despite minor issues. The clinic advised against using Minoxidil and Finasteride, and the user was satisfied with the initial results, planning to update progress at 12 months post-op.
The user experienced significant hair regrowth after three months of using 5 mg oral minoxidil nightly and plans to add finasteride to maintain progress. Many recommend combining minoxidil with finasteride or dutasteride to prevent future hair loss.
A 31-year-old Australian had a successful hair transplant in Turkey for $10,000 AUD, using minoxidil and finasteride to combat hair loss. He now has a full head of hair, increased confidence, and continues using finasteride with occasional minoxidil.
Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.
Finasteride and dutasteride are discussed for hair loss, with concerns about their effects on neurosteroids and potential side effects like depression. Alternatives like topical estrogen and lifestyle changes are considered, with varying opinions on mental health and hair regrowth.
The conversation discusses that dutasteride may be more effective than finasteride for frontal hair loss due to higher 5ar Type1 enzyme activity in that area. Some users question the validity of this information, while others confirm it with additional sources.
The conversation discusses how different factors can stimulate type1 and type 2 isoforms of 5-alpha reductase, which are enzymes linked to hair loss. Specific treatments mentioned include oral Dutasteride and topical Finasteride.
Minoxidil and finasteride may cause different shedding patterns; the user experienced shedding with finasteride which stopped, and is now concerned about potential shedding after starting minoxidil. They have been on finasteride for 3 months, minoxidil for 1 week, and had exosome therapy 1 month ago.
The user is experiencing continued hair thinning despite taking Finasteride 1 mg daily for over a year and is hesitant to try Minoxidil due to potential side effects and inconsistency. Suggestions include trying topical Minoxidil once a day, considering oral Minoxidil, and possibly getting a skin biopsy to determine the type of hair loss.
A user shared their positive experience with a 4750 graft hair transplant at Dr. Orçun Clinic in Istanbul, including a high-quality exosome treatment. Despite skepticism and accusations of advertising, the user expressed satisfaction with the natural-looking results and the doctor's personal involvement.
The hair transplant has a straight, unnatural-looking hairline that many find unappealing. The person is not using finasteride or minoxidil, which may affect future hair retention.
User experienced hair density decrease after 1 year of finasteride. Others shared similar experiences, suggesting it could be a temporary shed and discussed various treatments like dutasteride, minoxidil, dermaroller, and ketoconazole.
Low-Level Laser Therapy (LLLT) for hair loss is effective but requires consistent use and device replacement every 1-2 years. The treatment is costly, and results may not be permanent without continued use.
A 17-year-old experiencing hair loss, thinning, and white hair seeks advice on effective treatments. They have started using shampoo and conditioner but have not seen improvement and are open to product suggestions.
The user experienced worsening hair loss despite using finasteride and dutasteride. They are considering trying minoxidil but are unsure if it will help.
The user, SnooDonuts9235, shares their positive experience with a hair transplant and using topical finasteride and minoxidil. They express concern about increased shedding and ask if it is normal. Other users compliment their results and ask about the clinic and procedure details. SnooDonuts9235 encourages others to consider a hair transplant even without taking oral finasteride and shares that the procedure was not as scary as they initially thought.
GHK-Cu is a potent inhibitor of the type1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.
The user switched from topical to oral Minoxidil and Finasteride but saw no improvement after a year, with hair appearing thinner. They recently switched to Dutasteride, hoping for better results.
The user shared a 1.4-year hair growth journey using minoxidil and recently added micro-needling and finasteride, which significantly improved their hair. They also mentioned taking consistent photos for comparison and dermarolling once a week with a 1.5 mm needle.
Hair transplant results after 1 year discussed, with mostly positive feedback on density and appearance. User considers another surgery for hairline, but overall improvement noted.
Rosemary essential oil, particularly cineole, is considered by some to be beneficial for hair growth, though its effectiveness compared to minoxidil is debated. Finasteride, minoxidil, and ketoconazole shampoo are recommended treatments, while oils like rosemary and peppermint are seen as supplementary for scalp health.
The user shared a one-year progress of treating hair loss with finasteride, minoxidil capsules, and rosemary oil, and also improved mental health by addressing childhood trauma and changing negative thought patterns. Commenters congratulated the user on both hair regrowth and mental health progress, with one asking for advice on overcoming self-hatred and low confidence.
Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.
Microneedling depth should be customized based on hairtype and scalp area, with many users finding 0.5-0.6mm effective for miniaturized hairs to avoid damage. Users report varying pain levels and results, with some preferring shorter needle lengths and others using longer ones like 1.75mm for scalp health and density improvement.
Stopping dutasteride for a year caused significant hair loss, and resuming it with oral minoxidil led to only partial recovery. Users discuss treatments like finasteride, microneedling, and RU58841, noting mixed results and side effects.
A user shared progress pictures showing thicker hair after 8 months of using Fin/Min spray from HIMS. The conversation includes skepticism and humor from other users.
A user shared their 1.5-year experience using Minoxidil, a derma roller, and hair oil for hair loss, noting significant improvements in hair health and density. They also emphasized the importance of a healthier lifestyle and the positive impact of using a product combining Minoxidil with plant extracts.
A user switched from a 1.5 mm derma roller to an adjustable dermastamp for microneedling to treat hair loss and found it less painful and more effective. Some users prefer different depths and tools like the Dr.Pen for microneedling, while others debate the necessity of depth and tool type.