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      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

      community Hair Loss “Cure” for Inflammation: Topical Roflumilast

      in Research/Science  32 upvotes 3 months ago
      Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.

      community Almost 3 weeks on Pyrilutamide-Update

      in Update  12 upvotes 3 years ago
      The user has been using Actifolic Pyrilutamide 0.5% once daily for almost three weeks without noticing any side effects or progress. Other users suggest that significant results typically take 3-6 months to appear.

      community Hair Loss & Lipids: Why you have sebderm, folliculitis, LPP, inflammation, etc...

      in Research/Science  132 upvotes 1 year ago
      Excess sebum rich in cholesterol and triglycerides can lead to hair loss through inflammation, with treatments like Ciclopirox shampoo, Benzoyl Peroxide shampoo, and Clindamycin gel recommended for managing conditions like seborrheic dermatitis and folliculitis. Pioglitazone is suggested for Lichen Planopilaris, while Omega-3s and reducing processed foods may improve sebum quality, though genetic factors play a significant role.

      community My experience with Pyrilutamide

      in Update  3 upvotes 2 years ago
      The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  190 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

      in Chat  12 upvotes 2 years ago
      The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

      community Quitting Alfatradiol after 4 months

      in Product  4 upvotes 1 year ago
      The user stopped using Alfatradiol after 4 months due to no hair improvement and side effects like dry scalp and gallbladder pain. They are considering trying topilutamide, which is suggested as an alternative.

      community Update to losing hair at 16

      in Update  12 upvotes 6 years ago
      User has seborrhoeic dermatitis causing hair loss. They are using Ketoconazole shampoo and may use selenium sulfide shampoo.

      community Seborrheic dermatitis - can it cause long-term shedding (or telogen effluvium)?

      in Advice  5 upvotes 6 years ago
      A user is experiencing significant hair loss and scalp issues despite using Minoxidil, finasteride, and RU58841 since 2017. They switched to oral Minoxidil and are now on isotretinoin and topical corticosteroids for seborrheic dermatitis but continue to lose hair and seek advice on whether inflammation or treatment changes are the cause.

      community 1 year of treating my seb derm + minoxidil + microneedling

      in Progress Pictures  66 upvotes 11 months ago
      The user treated seborrheic dermatitis and hair loss with a routine including sulfate-free tea tree oil shampoo, ketoconazole shampoo, minoxidil foam, microneedling, and supplements like Omega-3 and Vitamin-D. They experienced significant hair shedding initially but saw improvement over a year.

      community DUPA, Non Responders and Connective Tissue Disorders

      in Research/Science  9 upvotes 11 months ago
      A 27-year-old male with diffuse hair loss, including the donor area, did not respond to finasteride, dutasteride, or minoxidil. He suspects his hair loss may be linked to a mild connective tissue disorder, possibly affecting the structural support of hair follicles, rather than being purely hormonal.

      community OND-1 "Cyclosporine A” New hair loss treatment

      in Research/Science  28 upvotes 4 weeks ago
      Orient Bio is developing a PLGA formulated version of Cyclosporine A to stimulate hair growth without its immunosuppressant effects. Users discuss various treatments like Clascoterone, PP405, minoxidil, and tacrolimus, expressing hope for new developments and sharing personal experiences with these treatments.

      community Topical spironolactone question

      in Product  2 upvotes 3 years ago
      User started using topical spironolactone on scalp and face, experienced fever feeling and sluggishness. Asks if side effects are normal or systemic.

      community The Worst Hair Loss Condition You (MAY) have: LPP

      in Research/Science  50 upvotes 1 year ago
      Lichen Planopilaris (LPP) is an autoimmune condition causing permanent hair loss and fibrosis, often misdiagnosed. Treatments include pioglitazone, topical corticosteroids, anti-inflammatory medication, and Jak inhibitors.

      community Spironolactone and pregnancy planning

      in Female  2 upvotes 1 year ago
      A user with AGA uses topical spironolactone 2% due to side effects from the oral form and is concerned about its use during conception and breastfeeding. They seek alternatives to prevent AGA relapse while planning pregnancy and after childbirth.

      community DUPA - Impossible to cure, so giving up

      in Update  3 upvotes 7 months ago
      The user diagnosed with DUPA tried treatments like dutasteride, finasteride, RU58841, and minoxidil without success and is considering a hair system. They hope for a future cure, possibly with PP405, and others suggest options like scalp biopsy and SMP.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  60 upvotes 1 month ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Minoxidil and seborrheic dermatitis

      in Minoxidil  5 upvotes 6 years ago
      Minoxidil use may worsen seborrheic dermatitis, causing itching and dandruff. Users consider stopping minoxidil or switching to foam to improve scalp condition.