community Is .5% kx-826 worthless? Koshine vs RU
Kx-826 at 0.5% shows limited effectiveness for hair loss, while 1% is more promising but expensive. RU58841 is considered a more feasible option until 1% kx-826 becomes affordable.
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960-990 / 1000+ resultscommunity Tretinoin absorption Minoxidil
Tretinoin may help more minoxidil convert to its active form and could potentially increase its absorption, raising concerns about safety if too much enters the bloodstream. It's unclear if tretinoin affects finasteride absorption.
community anti-androgens help with chronic seborric dermatitis ?! and hence diffuse thinning
An 18-year-old experiencing hair loss and seborrheic dermatitis has tried finasteride, dutasteride, and various shampoos without success. They are considering anti-androgens like RU58841 and KX-826 for oil control and dandruff reduction.
community Research about RU58841 /Why it was stopped
RU58841 showed promise for treating androgenic alopecia but research was halted due to financial and organizational changes. There were no significant safety concerns reported in human trials.
community 22M Exact three months of medication. Dut(0.5mg/day)+minox(2 times a day)+vitamin D (60k/week)
User took Dutasteride, Minoxidil, and Vitamin D for hair loss treatment and saw improvement in 2 months. Vitamin D deficiency played a role in recovery.
community For EU people: where do u get ru?
The conversation is about finding a source for RU58841 as a substitute for finasteride for hair loss treatment. Suggestions include Amazon and Anageninc.com.
community How to properly use and store RU58841?
The user is using RU58841, dutasteride, and minoxidil for hair loss, storing RU58841 in the fridge and applying it nightly. They report more baby hairs on the temples but are unsure if it's due to new growth or miniaturization, and seek advice on mixing and results from RU58841.
community The new Veritasium video made me conscious about a possible loss of effectiveness of DHT Inhibitors or Minoxidil
Concerns about the effectiveness of DHT inhibitors like finasteride and minoxidil due to potential polymorph issues. Experts suggest these concerns are largely unfounded, especially compared to rare cases like ritonavir.
community What happened to Breezula ????
The conversation discusses the effectiveness of a hair loss treatment called CB (Breezula) in comparison to Pyrilutamide, and its potential when combined with Finasteride. There is uncertainty about when or if phase 3 trials for Breezula will begin.
community I mixed ru58841 with minoxidil, help
OP mixed RU58841 with minoxidil and noticed undissolved particles. They are seeking advice on whether it matters or how to fully dissolve it.
community Megadosing Koshine826(Pyrilutamide), my Plan.
The user plans to use 1% Koshine826, 0.1% Alfatradiol, Minoxidil with Tretinoin, microneedling, and Stemoxydine for hair loss treatment. They expect significant recovery with this regimen.
community Severe Hair Loss Post-Surgery and Stress, Possible DUPA or Alopecia?
The user is experiencing severe hair loss after surgery and stress, with thinning all over the head, including the sides and neck. They are unsure if it's due to DUPA or alopecia areata incognita, and doctors have not observed miniaturization.
community Possible explaination for Finasteride Reflex Hyperandrogenicity
The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.
community How likely is it that my hair loss is due to vitamin D deficiency and stress?
A 19-year-old male suspects his hair loss is due to vitamin D deficiency and stress rather than genetics. Recommendations include taking finasteride, minoxidil, vitamin D, exercising, reducing stress, and consulting a doctor if needed.
community Finasteride raw powder storage
Store finasteride powder in a cool, dry place. RU58841 needs to be stored in the freezer.
community I’ve been on medications for 5 months now
A user has been using minoxidil, finasteride, derma stamping, and keto shampoo for hair loss for 5 months, noticing baby hairs but no thickening. Another user suggests trying topical magnesium chloride with UV light as an additional treatment.
community Progress since may 27, 2021. HairCAFE routine, DUT 3 times a week, topical minoxidil/tretinoin at night, topical stemoxydine and alfatradiol 50/50 mix with tretinoin in the morning.
User started DUT 3 times a week, topical minoxidil/tretinoin at night, and topical stemoxydine/alfatradiol mix with tretinoin in the morning for hair loss. They experienced significant progress and no side effects, crediting a YouTuber for encouragement.
community Is the Ru58841 hype justified?
RU58841 is debated for hair regrowth, with some users reporting no benefits and potential side effects, while others claim success when combined with dutasteride. Many suggest safer, well-researched treatments like finasteride and minoxidil for hair loss management.
community Why was fluridil abandoned and never made past phase 2?
Fluridil was abandoned due to its weak effectiveness and low binding affinity to the androgen receptor, making it less competitive against DHT and testosterone. Users discuss its limited results compared to other treatments like pyrilutamide and RU58841.
community Reaching the End
User tried dutasteride, topical finasteride, oral minox, dermawounding, saw palmetto, pumpkin seed oil, and ketacozonole for hair loss. Improvement was temporary, now trying RU58841 and seeking help.
community Should i do a hair transplant in my current state? Ive heard that HTs on diffuse thinners could kill existing follicles and be a net negative overall…Please help!
Considering a hair transplant for diffuse thinning may harm existing follicles. Treatments mentioned include Minoxidil, finasteride, and RU58841.
community RT1640 - Gray Hair Reversal Recipe
The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.
community Switch from fin to dut and its worse
Switching from finasteride to dutasteride can worsen hair loss for some men due to increased testosterone levels. Topical treatments like RU58841 and Pyrilutamide are suggested to counteract these effects, but individual responses vary.
community 2 months of minoxidil with 1 and a half months of microneedling, 1 month of ru58 and 10 days of topical minoxidil and finasteride.
The user shared progress pictures after 2 months of minoxidil, 1.5 months of microneedling, 1 month of RU58841, and 10 days of topical minoxidil and finasteride. They discussed their hair loss treatment regimen and results.
community Allopregnanolone deficiency by 5-ari inhibition (fin/dut users)
The conversation is about managing allopregnanolone deficiency caused by 5-alpha-reductase inhibitors like finasteride or dutasteride. Specific treatments discussed for hair loss include Minoxidil, finasteride, and RU58841.
community Pyrilutamide is available at Minoxidilmax
Minoxidilmax offering a 0.5% Pyrilutamide solution and debating the cost, effectiveness, and safety of using it alone or with other treatments such as Finasteride and Minoxidil.
community Safety of RU-58841: I talked to the Pharma Company that researched it, Human Clinical Trials, and Potential Reasons for Discontinuation
The safety and effectiveness of RU-58841 as a hair loss treatment, with some users reporting side effects like chest pains, while others had positive results. The original research on RU-58841 was likely stopped due to financial issues, not safety concerns.
community Testosterone, gray hair, low vitamin D, and switching to oral Minoxidil
A woman experiencing hair loss due to high testosterone and low vitamin D is using treatments like Dutasteride, Rogaine, zinc, ketoconazole shampoo, dermastamp, iRestore, multivitamins, scalp massager, and vitamin D. She plans to switch to oral Minoxidil under medical supervision.
community Who here uses alfatradiol? Anybody having success with this? Please share your experience
The conversation is about using alfatradiol for hair loss treatment. One user combined it with oral finasteride but noticed no significant difference.
community 8 months - 0.5mg dut, 80mg Ru58841, 5mg oral min, topical min at night, microneedle 1.5mm every other week
The conclusion of the conversation is that the user has experienced significant hair regrowth using a combination of medications, including dutasteride, RU58841, and minoxidil. They have not experienced any noticeable side effects and are considering a hair transplant in the future.