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      community Dutasteride treatment in female 6 months

      in Treatment  4 upvotes 2 years ago
      A user reported worsening hair shedding and thinning after 6 months of daily dutasteride, despite also using minoxidil, bicalutamide, and recently adding RU58841. They are considering stopping dutasteride due to lack of improvement.

      community A Short Recap on PP405 and AAD 2026

      in Update 3 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community Experience with CB (Breezula)?

      in Research/Science  4 upvotes 6 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community Reducing DHT levels naturally. Anyone getting good results?

      in Treatment  4 upvotes 2 years ago
      Natural alternatives like omega-3, green tea, and pumpkin seeds are suggested for reducing DHT levels, but their effectiveness is questioned. Topical minoxidil and ketoconazole shampoo are recommended, with some users also considering low-dose finasteride and saw palmetto.

      community (Europe) looking for advice on topical anti androgen use

      in Treatment  3 upvotes 11 months ago
      The user is using finasteride, minoxidil, and ciclopirox shampoo for hair loss and is considering adding a topical anti-androgen like RU58841, Clacosterone, or KX286. They have scheduled a hair transplant and are concerned about the cost and effectiveness of future treatments.

      community Fin is killing my eyes. Alternatives?

      in Treatment  6 upvotes 2 years ago
      A user experienced severe dry eyes as a side effect of using topical and oral Finasteride for hair loss and is seeking alternative treatments. They are considering other anti-androgens like Dutasteride, RU58841, Pyrilytamide, and Fluridil, despite mixed results and potential side effects.

      community RU58841 dilution in Minoxidil Vs PG+Ethanol

      in Treatment  5 upvotes 2 years ago
      RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.

      community Pelage PP405 Phase 2a completed.

      in Research/Science  61 upvotes 5 months ago
      Minoxidil, finasteride, and RU58841 are discussed as treatments for hair loss, with excitement around a new drug, PP405, and a reformulated oral minoxidil in trials. Concerns about cost, side effects, and long-term use are also mentioned.

      community DHT Blocker without Selenium and Zinc??

      in Female  6 upvotes 1 year ago
      A female user is seeking a DHT blocker without Selenium or Zinc due to hair breakage and is currently using Saw Palmetto, Nature's Bounty Hair, Skin and Nails, Pumpkin seed oil, Dermastamp, and Pura D'or products. She has tried Minoxidil without success and is considering Finasteride but prefers natural options first.

      community Is dutasteride not working for me?

      in Progress Pictures  1 upvotes 8 months ago
      The user is experiencing prolonged hair shedding despite using Dutasteride, Xpecia, Ocean Capilus, and microneedling. They are considering adding minoxidil due to concerns about the effectiveness of their current regimen.

      community My endless RU58841 cycle [experience thread)

      in Update  10 upvotes 2 years ago
      The user experienced hair loss and itching after stopping RU58841 and resumed it to stop these symptoms. They also use Dutasteride and question which treatment is effective.

      community Discount on RU58841 at Anagen Inc with coupon code - FYI

      in Product  6 upvotes 1 year ago
      A user shared a discount code for RU58841 from Anagen Inc, which some users find effective for hair loss without side effects. Another user expressed skepticism about the safety of RU58841 due to limited research.

      community Pyrilutamide phase III clinical trial results released

      in Research/Science  31 upvotes 2 years ago
      Pyrilutamide did not show effectiveness in regrowing hair compared to a placebo, but it may still help maintain existing hair by preventing DHT from causing follicle miniaturization. Some users believe it could be beneficial when used with other treatments like minoxidil, finasteride, and dutasteride.

      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 2 years ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 6 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.