Search

everythinglearnresearchcommunity

for

Search:↓

The conversation discusses using RU58841, topical finasteride/minoxidil, MK677, and microneedling as treatments for hair loss. MK677 is mentioned as a growth hormone that improves hair health and recovery from microneedling.

The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.

A 19-year-old has seen hair regrowth after 10 months using finasteride and recently added minoxidil and tretinoin. They experienced no side effects from the treatments and are optimistic about further improvement.

PP405 shows promise in treating severe hair loss, with 31% of users experiencing over 20% hair density increase in four weeks, faster than minoxidil and finasteride. Some users are skeptical about the results' significance and long-term efficacy.

A person suspects their friend had a hair transplant instead of stem-cell injections due to a noticeably straight hairline. The discussion includes opinions on hair transplants, societal perceptions, and suggestions like using finasteride to maintain hair.

The user is experiencing gradual hairline regrowth with finasteride and is considering increasing the concentration of topical finasteride and minoxidil to speed up growth. They are also using microneedling and considering adding tretinoin to their routine.

The conversation is about experimenting with microneedling and growth factor topicals for hair growth, avoiding Minoxidil due to shedding concerns. The treatment includes microneedling, growth factor topicals, finasteride, biotin, and a caffeine shampoo.

Hair loss treatments like Minoxidil, finasteride, and potential mRNA therapies are discussed. There is skepticism about targeting specific genes due to the complex genetic nature of hair loss.

The conversation is about a person who underwent a hair transplant surgery after using Rogaine, finasteride, and Nutrafol. They received 2300 grafts and discussed the appearance and density of the transplant, with mixed opinions on the results and advice on future procedures.

The conversation is about hair loss treatments, specifically the anticipation for the release of a new treatment, GT20029, by 2028. Users are discussing their experiences with current treatments like finasteride and dutasteride, and the potential of future treatments, including FAK inhibitors and verteporfin trials.

The conversation is about hair regrowth using topical finasteride, minoxidil, and microneedling, with some users noticing new hair growth. The original poster also takes protein, biotin, and vitamin D supplements and prefers topical treatments due to concerns about side effects from oral finasteride.

A user shared a blog post by "swissTemples" claiming to have reversed hair loss using a combination of treatments including suppressing PGD2 and increasing PGE2. The user noted that "swissTemples" has been banned from forums, possibly due to conflicts of interest.

A 40-year-old using 1mg finasteride daily reports noticeable hair regrowth in 7 weeks and plans to start 5% minoxidil and microneedling. Feedback is mixed, with some seeing progress and others suggesting a hair transplant.

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

Veradermics' phase 2 trial of slow-release oral minoxidil shows promising hair regrowth with minimized side effects, gaining significant attention and funding. PP405 is also noted for its potential as a side-effect-free alternative.

PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.

After a hair transplant, it's advised to stop using RU58841 and minoxidil to avoid irritation, resuming them 25-30 days post-surgery if the scalp is healed. The user is currently using finasteride, minoxidil, and RU58841, but there are concerns about the safety and efficacy of RU58841 in humans.

A 21-year-old shares their one-year progress using finasteride for hair loss, experiencing initial shedding but eventual regrowth, especially on the crown. They consider switching to dutasteride due to continued hair loss at the front temple and mid-scalp areas.

The user experienced significant hair regrowth over eight months using topical minoxidil twice daily and 1mg oral finasteride daily. They also mentioned using a DHT blocker to aid regrowth.

A user shared their hair transformation over four months using daily 2.5mg oral minoxidil, every other day 1mg oral finasteride, weekly dermastamping, and daily scalp massages, with plans for a hair transplant. Another user suggested continuing the medication for a year before considering a transplant.

CB-03-01 is a topical anti-androgen with low absorption, offering potential as a side-effect-free alternative to Finasteride/Dutasteride for hair loss. It's in stage 2 clinical trials for acne and showing promise for male pattern baldness.

Adding tretinoin to minoxidil may help non-responders but likely won't improve results for those already responding to minoxidil. The user plans to try tretinoin with minoxidil and finasteride to see if it enhances hair regrowth.

A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

A 29-year-old man had a successful hair transplant at Dr. Ulusan Clinic in Izmir, Turkey, receiving over 4600 grafts and exosome injections. He started using finasteride and minoxidil daily a month after shaving his head, which improved his confidence and outlook on life.

A 24-year-old male is considering the "Big 4" treatments (Finasteride, Minoxidil, Ketoconazole shampoo, and Microneedling) or a hair transplant for hair loss. Most users recommend starting with Finasteride and Minoxidil to stabilize hair loss before considering a transplant.

A 23-year-old male has been experiencing hair loss since 2022 and has used minoxidil and dutasteride with reduced shedding but no hair regrowth. He is considering PRP with mesotherapy and red light therapy, GFC, or exosomes, with a preference for exosomes due to efficiency and a reputable clinic.

A 29-year-old is using oral minoxidil, finasteride, hormone replacement therapy (HRT), and microneedling for hair regrowth. They started balding at 20, worsened at 25, and are transitioning with testosterone blockers.

A 17-year-old has been using minoxidil, microneedling, and finasteride for hair loss, with added tretinoin for better absorption. They are seeking opinions on their progress and the use of finasteride as a teenager.

Minoxidil and finasteride work through different mechanisms; minoxidil-dependent hair requires continued use to maintain growth, while finasteride prevents further hair loss but cannot sustain minoxidil gains alone. Current treatments like minoxidil, finasteride, and others need indefinite use, as no permanent solution exists yet.

A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.