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      community Pyrilutamide update number 2 - 2 week use

      in Update  174 upvotes 3 years ago
      An update on the use of Pyrilutamide, a new drug for hair loss, which has resulted in no shedding or testicle ache; other users have questioned the science behind this and shared their own experiences with Finasteride, Minoxidil, and microneedling.

      community Vitamin D advice I received after seeing my blood work.

      in Research/Science  88 upvotes 4 years ago
      The conversation discusses the importance of taking vitamin D with food for better absorption and its potential role in hair loss. Some users also suggest taking vitamin D with K2, getting sunlight, and using finasteride for hair loss treatment.

      community Tretinoin for better Minoxidil response

      in Treatment  11 upvotes 5 years ago
      The conversation is about using tretinoin to improve the response to Minoxidil for hair loss treatment. No specific protocol for tretinoin application is provided.

      community Green tea/ soy Isoflavones supplements for MPB

      in Product  4 upvotes 5 years ago
      Green tea extract and soy isoflavones may help with hair loss by inhibiting DHT and providing additional health benefits. Combining these with finasteride and possibly using nizoral shampoo could enhance effectiveness in managing hair loss.

      community Winlevi coming out in 2019

       13 upvotes 7 years ago
      The conversation discusses the potential release of Winlevi in 2019 by Cassiopeia for hair loss treatment. It suggests a regimen combining minoxidil, Winlevi, Nizoral, and possibly dermarolling, with a comment mentioning Breezula as an alternative to finasteride without side effects.

      community Thinking to start fin

      in Finasteride  4 upvotes 8 years ago
      The conversation discusses starting finasteride for hair loss, addressing concerns about side effects, dosage, and travel with the medication. It suggests taking the pill without overthinking side effects and reassures that carrying it on a plane is generally not an issue.

      community Using minoxidil for 6 months. Not seeing results

      in Minoxidil  111 upvotes 3 months ago
      Minoxidil alone is not effective for hair regrowth; adding a DHT blocker like finasteride or dutasteride is recommended. Dermastamping and micro-needling can enhance results, and some users suggest trying oral minoxidil or natural DHT blockers.

      community Pelage are going to do two phase 3 trials for PP405. How long will it take to complete two phase 3 trials?

      in Chat  45 upvotes 5 months ago
      Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

      community How many years can we expect PP405 to be on the market

      in Product  12 upvotes 10 months ago
      PP405 is expected to be on the market between 2027 and 2030, with phase 3 trials starting in 2026. There is skepticism about its fast-tracking due to its cosmetic nature, and it may appear on the gray market sooner.

      community Use minoxidil & finasteride. It works.

      in Minoxidil  555 upvotes 10 months ago
      Minoxidil and finasteride effectively improve hairlines and reduce balding, though some users report side effects like reduced libido. Consistent use over 1-2 years leads to significant hair regrowth, with some users also using skincare and biotin for added benefits.

      community PP405 timeframe ? Could it replace current treatments ?

      in Update  34 upvotes 11 months ago
      PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.

      community The Fear of Oral Minoxidil is Overblown

      in Research/Science  272 upvotes 11 months ago
      Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

      community What is the cause of "DHT itch"?

      in Research/Science  7 upvotes 1 year ago
      The conversation discusses the effects of using Tongkat ali and dioscorea to raise DHT levels, leading to increased body hair growth and an itchy scalp, without causing hair loss. The discussion also debates the role of DHT in male characteristics and its impact on sexual function, with differing opinions on its importance and effects.

      community New warning by FDA on topical finasteride

      in Research/Science  194 upvotes 1 year ago
      The FDA warned that topical finasteride can cause serious side effects like sexual dysfunction and brain fog, similar to oral finasteride. Compounded topical formulations pose additional risks due to lack of regulation.

      community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

      in Research/Science  4 upvotes 1 year ago
      Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

      community 2Y 5M on dut, ask me anything

      in Finasteride/Dutasteride  130 upvotes 1 year ago
      A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.