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      community Weird response to microneedling

      in Microneedling  40 upvotes 1 year ago
      Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.

      community Drastic and sudden change in hair loss condition

      in General  76 upvotes 1 year ago
      The user experienced increased hair loss and scalp itchiness despite using finasteride and plans to resume minoxidil and start microneedling. They are considering using clay, Aveda thickening tonic, and a beanie to manage the appearance of thinning hair.

      community At Home Dutasteride Mesotherapy

      in Chat  5 upvotes 1 year ago
      The user is starting Dutasteride mesotherapy and seeks advice on whether to apply the solution immediately after microneedling or wait 12-24 hours. They couldn't find instructions for first-timers.

      community Switching from oral to topical dut

      in Finasteride/Dutasteride  1 upvotes 2 months ago
      Switching from oral to topical dutasteride can cause shedding due to changes in DHT levels, and it's recommended to overlap both treatments to minimize this effect. Topical dutasteride may cause scalp irritation, and the user is considering dutasteride mesotherapy as an alternative.

      community Clascoterone study going on right now

      in Research/Science  352 upvotes 1 year ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community Anybody try Duderma from min max?

      in Finasteride/Dutasteride  1 upvotes 9 months ago
      A user is using topical dutasteride, topical finasteride, and minoxidil to address a receding hairline and is seeking opinions on their routine. They report seeing vellus hair growth after nearly three months of use.

      community Depressed that topical dut+min is causing unwanted hair everywhere on my face. Is there anything can I do?

      in Minoxidil  21 upvotes 2 years ago
      The conversation is about a user experiencing excessive hair growth on their body due to using topical minoxidil and dutasteride. The suggested solutions are shaving off the excess hair or considering laser epilation. It is mentioned that dutasteride does not cause extra hair growth, while minoxidil can stimulate hair growth in unintended areas. The user is advised to lower the dosage, concentration, or frequency of use and only apply the treatment to the desired areas.

      community Terminal hairs growing in, but derm still says I’m going to go bald in the years to come??

      in Chat  6 upvotes 10 months ago
      A 30-year-old woman with a history of anemia and low vitamin D experienced hair shedding, which improved after addressing nutrient deficiencies. Despite regrowth of terminal hairs, her dermatologist recommended treatments like minoxidil and spironolactone to prevent future bald spots, but she is cautious due to family history of hormone-related cancers.

      community 10 months treating MPB - I am happy with these results

      in Progress Pictures  8 upvotes 9 months ago
      A 26-year-old man shared his positive results after 10 months of treating male pattern baldness using a regimen that includes Estradiol Enanthate, DHPA, Bicalutamide, Dutasteride, oral and topical Minoxidil, and a dermaroller. He experienced mild gynecomastia and reduced body hair as side effects but was satisfied with the outcome.

      community No side effects on pyrilutamide / KX-826 so far

      in Research/Science  208 upvotes 4 years ago
      User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

      community Still thinning on dut + oral min

      in Treatment  12 upvotes 2 months ago
      A 26-year-old is experiencing worsening hair thinning despite using dutasteride 0.5 mg and oral minoxidil 5 mg, alongside ketoconazole for seborrheic dermatitis. Users suggest patience, as results may take 12–18 months, and consider increasing the dutasteride dosage or consulting a dermatologist.

      community The Truth About DUPA and Retrograde: My Research Summary

      in Research/Science  19 upvotes 1 year ago
      The conversation discusses the importance of scalp biopsies for diagnosing hair loss conditions like DUPA and Retrograde, which may not be just AGA. It emphasizes that treatments like finasteride and dutasteride may not work if the condition is autoimmune.

      community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

      in Research/Science  1 upvotes 2 weeks ago
      AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 5 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community PYRILUTAMIDE VS RU58841 users which is superior

      in Update  27 upvotes 3 years ago
      Hair loss treatments, with users discussing their experiences with both RU58841 and Pyrilutamide, noting that the latter has only recently become available but may yield better results in the long term.

      community EU topical melatonin recommendations?

      in Treatment  7 upvotes 3 months ago
      The conversation discusses recommendations for using topical melatonin for hair loss treatment. It also mentions Minoxidil, finasteride, and RU58841 as other treatments.

      community 6 weeks on topical dut/min/tret

      in Progress Pictures  32 upvotes 1 year ago
      The user is seeing progress in hair regrowth using a combination of 8% minoxidil, 0.25% dutasteride, and 0.01% tretinoin. The conversation includes comments on the effectiveness and application of these treatments.

      community Pyrilutamide application questions

      in Treatment  3 upvotes 2 years ago
      Sprocketshead asks if pyrilutamide can be applied with minoxidil, and inquires about its consistency and odor. They want to know if it's more high maintenance than topical minoxidil.

      community Has anyone else seen this encouraging verteporfin case study?

      in Progress Pictures  34 upvotes 2 years ago
      The conversation discusses the potential use of verteporfin for hair loss treatment, with one user mentioning their surgeon's interest in trying it and another noting its research status and clinical use as a YAP inhibitor. Some users debate the market size, availability of generics, and the optimism in the hair loss community regarding new treatments.