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      community White hair seemed to be turn black, re-pigmentation

      in Update  1 upvotes 7 months ago
      The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community 1MG Fin 14 Months Results

      in Finasteride/Dutasteride  160 upvotes 5 years ago
      A user's 14-month journey with finasteride, microneedling, and Nizoral to treat hair loss. They experienced some side effects such as ball ache, needing to pee constantly, and less semen, but the results were generally positive.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Is RU58841 worth it? Has anybody seen success on it?

      in Technology  6 upvotes 3 months ago
      RU58841 is used by some for hair loss, with mixed results; one user reported success with no side effects, while another experienced lung and heart issues. RU58841 is often sourced from third-party vendors and used alongside treatments like dutasteride and minoxidil.

      community Pyrilutamide update number 1 - 1 week use

      in Update  55 upvotes 3 years ago
      A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

      community GT-20029 should be much more superior than finasteride

      in Research/Science  44 upvotes 1 year ago
      GT-20029 is discussed as a potential hair loss treatment, with concerns about its safety and systemic absorption compared to finasteride. Users express skepticism about its effectiveness and safety, noting that it may not surpass existing treatments like finasteride and minoxidil.

      community Before and after adding pyrilutamide and alfatrodial

      in Progress Pictures  69 upvotes 1 month ago
      A user shared their experience with hair loss treatments, using minoxidil, pyrilutamide, alfatrodial, and nizoral to improve hair density and thickness. They reported positive results without side effects and emphasized the importance of consistency with topical treatments.

      community Ru58841 made my hair worse

      in General  138 upvotes 1 year ago
      RU58841 worsened hair condition, causing thinning and unusual patterns. The user stopped using it two months ago but hasn't seen recovery, and there's speculation about androgen receptor upregulation.

      community P5P supplementation for fin sides.

      in Treatment  7 upvotes 4 years ago
      P5P supplementation helped reverse finasteride side effects, particularly by lowering prolactin levels and restoring sensitivity. The user experienced significant improvement within a day and full recovery in a few days.

      community Ligand Chem cease trading Pyrilutamide

      in Product  14 upvotes 3 years ago
      Pyrilutamide, a possible hair loss treatment, ceasing to be traded due to patent laws; and the hope that this indicates it may be a legitimate treatment.

      community Pyrilutamide or RU or cb-03-01?

      in Minoxidil  2 upvotes 6 months ago
      The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

      community Please critique my regimen, gentle approach oral/topical

      in Treatment  1 upvotes 2 years ago
      The user is taking 0.5mg finasteride and 0.5mg Loniten orally daily, using Eucapil twice weekly, and Minoxidil foam once daily for hair loss. They believe Eucapil effectively stops hair loss despite side effects like breast growth.

      community My current nuclear stack. Thoughts?

      in Chat  7 upvotes 2 years ago
      The user is using RU58841 twice daily, dutasteride 0.5mg every two days, dutasteride mesotherapy every three months, and 20mg oral minoxidil daily. Other users suggest this regimen is excessive and recommend adding microneedling and ketoconazole shampoo.

      community Recommend stemoxydine as an adjunct therapy

      in Treatment  4 upvotes 2 years ago
      The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.

      community Finasteyd topical 0.025% minoxidil and caffeine action

      in Progress Pictures  102 upvotes 1 year ago
      The user "OP" uses a combination of topical minoxidil 5%, finasteride 0.025%, and caffeine to combat hair loss, with noticeable results over 5-6 months. Side effects include unwanted body hair growth and an itchy scalp, but no significant sexual side effects.

      community Topical solution recommendation

      in Treatment  2 upvotes 10 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community Alfatradiol Experience (2 months)

      in Treatment  12 upvotes 5 years ago
      User experienced side effects from oral finasteride and tried topical Alfatradiol for hair loss. Alfatradiol provided maintenance without significant regrowth, and user suggests it as an alternative for those struggling with finasteride side effects.

      community Pyrilutamide ,the molecule’s true nature

      in Research  302 upvotes 1 year ago
      Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.