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      community How long is RU58841 active after application

      in Research/Science  1 upvotes 1 year ago
      RU58841 remains active for several hours after application, and it's suggested to wait a few hours before washing it off to maintain its effectiveness. There is a concern about potential transfer to others if they touch the hair shortly after application.

      community He is claiming, he can treat alopecia

      in Chat  357 upvotes 3 months ago
      A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

      community Question about Ru58841 regarding the dose

      in Treatment  3 upvotes 2 years ago
      A 21-year-old with diffuse thinning hair is considering RU58841 due to side effects from topical finasteride and is asking for the lowest effective dose and time to see results from RU58841 users.

      community Alfatradiol only for mild thinning

      in Product  1 upvotes 5 months ago
      Alfatradiol is considered safe but less effective than finasteride for hair loss. One user reported subtle regrowth using alfatradiol with finasteride and minoxidil, while another found alfatradiol ineffective.

      community IT ACTUALLY WORKED - 9 month Dut + Min update

      in Progress Pictures  443 upvotes 2 months ago
      A user shared successful hair regrowth results after 9 months using 0.5mg Dutasteride and 2.5mg Minoxidil daily, with no side effects. The user chose Dutasteride over Finasteride for its potency and perceived lower side effects.

      community is anyone using ru58841 against acne?

      in Technology  3 upvotes 1 year ago
      RU58841 is discussed as a potential treatment for acne and hair loss, with users debating its effectiveness and safety compared to other treatments like finasteride, minoxidil, and dutasteride. Concerns about RU58841's side effects and lack of clinical trials are raised, while some users share their personal experiences and routines involving RU58841 for hair loss.

      community Legit Chinese bulk RU58841 powder sources

      in Product  5 upvotes 2 months ago
      The conversation is about finding a legitimate and affordable Chinese source for RU58841 powder for hair loss treatment. It suggests choosing a vendor with good reviews and testing the product for authenticity.

      community any Ru58841 user ? + What do I need to expect?

      in Product  10 upvotes 1 year ago
      The user is considering adding RU58841 to their current hair loss treatment of finasteride and minoxidil, but is concerned about potential side effects like hairline recession and shedding. Some users report positive results with RU58841, while others experience side effects such as chest pain and dizziness.

      community RU58841 dilution in Minoxidil Vs PG+Ethanol

      in Treatment  4 upvotes 2 years ago
      RU58841 mixed with Minoxidil seems less effective over time, so the user plans to switch to a PG and Ethanol dilution for better results. They also consider using rosemary oil with Minoxidil to enhance RU58841 absorption.

      community Does pyrilutamide actually work?

      in Treatment  24 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment, and how it compares to existing treatments such as Minoxidil, Finasteride and RU58841. Real-world results are being discussed to determine its effectiveness.

      community Can I start dut and ru at the same time

      in Finasteride/Dutasteride  2 upvotes 3 months ago
      The user has been using finasteride for almost two years but is considering switching to dutasteride and is curious about adding RU58841. They decide to stick with dutasteride due to concerns about RU58841's safety.

      community Why are low finasteride doses seen as highly ineffective, when studies show 0.05 mg/day to work?

      in Finasteride/Dutasteride  38 upvotes 3 years ago
      The efficacy of low doses of finasteride to reduce scalp DHT, and whether studies showing a 61% reduction are reflected in actual results. Replies discussed hair growth as an unintended consequence of minoxidil and finasteride use, as well as self-selective bias, potential side effects, and that studies measure effectiveness by hair count changes rather than DHT inhibition.

      community Shiseido RCH-01

       7 upvotes 7 years ago
      Shiseido RCH-01 and Replicel's upcoming trial data release. Users discuss expected release timelines and clarify quarter dates.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  252 upvotes 3 years ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community Why us no one talking about this?

      in Treatment  63 upvotes 4 months ago
      A new hair loss treatment reportedly shows a 539% improvement in hair count, but skepticism remains due to unclear placebo results and potential minimal actual hair growth. Many users doubt its effectiveness and market viability, citing high costs and lack of visual proof.

      community Replicel, worthy of hype or probable disappointment? Questions thread

       4 upvotes 9 years ago
      The conversation discusses the potential of Replicel/Shiseido treatment for hair loss, questioning its effectiveness, whether it grows new follicles, and its market release timeline. It also compares Replicel to other competitors like Kyocera/RIKEN/Tsuji.

      community 8.5 month progress of min/fin/RU

      in Progress Pictures  62 upvotes 5 years ago
      The conversation discusses an 8.5-month progress of using Minoxidil, Finasteride, and RU58841 for hair loss. People are complimenting the user on the significant improvement in hair thickness.

      community Is this VIOFAIRY Minoxidil brand good

      in Minoxidil  2 upvotes 1 year ago
      A user has been using a new brand of minoxidil called VIOFAIRY for six months and finds it effective, though the labeling has misspellings. They are seeking feedback from others who have tried this brand.

      community What’s your experience with RU58841?

      in Treatment  21 upvotes 2 years ago
      People shared mixed experiences with RU58841 for hair loss; one person saw no improvement, another had significant gains and uses it with finasteride, while a third had an allergic reaction to the premixed solution. Some mix RU58841 powder into minoxidil themselves.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community I ingested RU58841 orally to see if its legit

      in Chat  131 upvotes 10 months ago
      A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 2 years ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.