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      community Counter-update: Cbum's transplant DOESNT look super good now

      in Transplants  221 upvotes 10 months ago
      Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.

      community Topical spironolactone question

      in Product  2 upvotes 2 years ago
      User started using topical spironolactone on scalp and face, experienced fever feeling and sluggishness. Asks if side effects are normal or systemic.

      community Sometimes the hair loss was in our control the whole time

      in Chat  831 upvotes 6 months ago
      The conversation discusses hair loss and the potential impact of diet and lifestyle changes, particularly increased protein intake, on hair health. The original poster shared their experience of improved hair appearance after weight loss and dietary changes, despite skepticism from others about lighting differences in photos and the effectiveness of diet alone without finasteride or minoxidil.

      community Hair loss - The Root of the Problem

      in Hair Systems  2 upvotes 5 years ago
      Hair loss can be influenced by nutritional deficiencies, particularly low Vitamin D and fatty liver, and improving nutrition and lifestyle can strengthen hair. Treatments suggested include regular exercise, a balanced diet, vitamin supplements, and coconut oil massages, while acknowledging that hereditary factors may also play a role.

      community My dermatologist gave me Ell cranell?

      in Treatment  4 upvotes 2 years ago
      The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.

      community PSA: Greasy, product laden hair makes the scalp 10x more visible

      in Treatment  30 upvotes 1 year ago
      Greasy or product-laden hair can make the scalp appear more visible, leading some to mistakenly think they are balding. Proper hair washing and avoiding heavy products can help assess true hair thickness, and treatments like finasteride are used by some for actual hair loss.

      community Water retention from topical minoxidil

      in Minoxidil  4 upvotes 4 years ago
      Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.

      community Extreme regimen and still miniaturized hairs. AGA is just impossible to beat.

      in Insane  32 upvotes 3 years ago
      A user's extreme regimen for hair loss, which includes taking oral and topical medications such as minoxidil, dutasteride, cyproterone acetate and bicalutamide, but still experiencing miniaturization. Suggestions were made to try other treatments such as RU58841 and Pyrilutamide, while also considering mental health treatment and advice on lookmaxxing.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 2 years ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community B12 deficiency hairloss (hair thinning)

      in Treatment  7 upvotes 7 months ago
      Hair loss due to vitamin B12 deficiency is discussed, with some users suggesting supplements and dietary changes, while others recommend medications like finasteride or dutasteride. The conversation highlights differing opinions on the cause of hair loss, with some attributing it to genetics or male pattern baldness.

      community Using WinLevi (Clascoterone) for Seborrheic Dermatitis and Acne

      in Treatment  4 upvotes 2 years ago
      Winlevi (clascoterone) is discussed as a treatment for hormonal acne and seborrheic dermatitis due to its ability to block DHT and regulate sebum production. The post suggests that Winlevi could offer a novel approach for managing seborrheic dermatitis.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Best Treatment In The Pipeline?

      in Chat  15 upvotes 1 year ago
      New treatments for AGA are emerging, including pyrilutumide, gt0029, scube3, kx-826, and pp405. Verteporfin is mentioned as a promising option.

      community Binding affinity of pyrilutamide!

      in Update  169 upvotes 3 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.

      community Verteporfin (Visudyne) group buy 🌷

      in Treatment  29 upvotes 4 years ago
      User seeks participants for Verteporfin group buy. Verteporfin, FDA approved, may regenerate hair follicles and sweat glands through heavy microneedling.

      community 26F Thinner hair due to vitamin deficiencies?

      in Female  11 upvotes 2 years ago
      A female user with chronic anemia and vitamin deficiencies is experiencing finer, straighter hair and seeks recommendations for scalp products to improve circulation and prevent potential hair thinning. She is considering growth oils but is unsure of their effectiveness.

      community Why is dutasteride's volume of distribution so much bigger than finasteride? Is it more lipophilic and crosses barriers better?

      in Finasteride/Dutasteride  23 upvotes 1 year ago
      Dutasteride has a larger volume of distribution than finasteride due to its lipophilic nature, allowing it to concentrate in hydrophobic areas and making it difficult to excrete. A user experiencing hair loss has been using oral finasteride for 10 months with minimal regrowth and is considering switching to dutasteride or adding oral minoxidil.

      community Vitamin D deficiency - could it be the cause?

      in Update  6 upvotes 11 months ago
      The user is experiencing hair thinning and has a vitamin D deficiency, which they suspect might be causing the issue, but they are also considering androgenic alopecia (AGA) as a cause. They are currently using minoxidil and are unable to get finasteride prescribed, while others suggest addressing the vitamin D deficiency and consulting a dermatologist.