PP405, a topical LDH inhibitor, has shown to stimulate hair follicle stem cell proliferation in humans with moderate hair loss. They are advancing to more detailed trials this year.
Vitamin E and K deficiencies due to exocrine pancreatic insufficiency may affect hair growth. A scalp biopsy is recommended to check for autoimmune-related hair loss.
Oral minoxidil is generally more effective than topical minoxidil, despite higher side effect risks. Topical minoxidil can achieve higher bloodstream levels in some individuals, but effectiveness depends on conversion and scalp response.
The conversation discusses a botanically derived treatment for androgenetic alopecia using ingredients like saw palmetto, green tea, and evening primrose, showing impressive results over 270 days. Concerns include the study's uncontrolled nature and potential product motivation, with suggestions to enhance absorption through derma rolling.
The user improved their hair loss from a Norwood scale 2.5/3 to 1.5/2 using treatments including 2.5 mg dutasteride, RU58841, 15 mg oral minoxidil, isoflavones, NAC, pumpkin seed oil, NAD+, and Vipelin, but still experiences temple recession. Other users expressed concern over the high dosages of oral minoxidil and dutasteride.
User asks if washing hair or using hair fibers after minoxidil dries is okay and if dry scalp means full absorption. Some doctors and sources say 50-75% absorption occurs after an hour.
A user shared a homemade hair loss treatment spray containing minoxidil, Japanese Sato Arovis, essential oils, and isopropyl alcohol, used alongside microneedling. They experienced initial shedding followed by strong hair regrowth after five months of use.
The conversation is about using castor oil for hair loss treatment alongside finasteride and minoxidil. Users discuss the method of consuming castor oil, its potential side effects, and question its effectiveness for hair growth.
The user has been using 1 mg finasteride, topical minoxidil twice daily, 1 biotin vitamin, and a 0.5 mm dermaroller for hair loss treatment since April. They've seen progress but experienced a shedding event in October, and are hoping for increased density in the coming months.