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      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  215 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community Any other treatments to still be hopeful for?

      in Research/Science  20 upvotes 2 years ago
      The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

      community On fin and min for 8 years and always still feel like I have "ghost hair"

      in Chat  16 upvotes 1 month ago
      The user has been using finasteride and minoxidil for 8 years and recently started dutasteride, but still experiences thin, see-through hair. Suggestions include adding probiotics, changing hairstyle, checking hormones, supplementing vitamin D3, trying laser therapy, and improving gut health.

      community RU55481

       4 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.
      Is my hairline starting to minituarize?

      community Is my hairline starting to minituarize?

      in General  117 upvotes 7 months ago
      The conversation discusses concerns about potential hairline miniaturization and whether to start finasteride as a preventive measure. Recommendations include consulting a specialist and considering treatments like finasteride, dutasteride, minoxidil, and ketoconazole.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community My 1 week experience on Pyrilutamide only

      in Treatment  14 upvotes 3 years ago
      User Arrosis shared their 1-week experience using Pyrilutamide for hair loss, noticing reduced shedding and increased libido but also experiencing headaches, dizziness, and nipple sensitivity. They plan to try a lower frequency to see if it helps with side effects.

      community A Short Recap on PP405 and AAD 2026

      in Update 2 months ago
      PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

      community topical exosomes - experimenting

      in Treatment  1 upvotes 3 months ago
      The conversation is about experimenting with topical exosomes for hair loss treatment, alongside microneedling, Happy Head's gel-like topical, and Ordinary's hair serum. The user also mentions the availability of treatments like latanoprost and Redensyl.

      community A prayer for our lord and saviour

      in Product  32 upvotes 1 year ago
      The conversation is a humorous and hopeful prayer for the effectiveness of finasteride in combating hair loss. Participants express gratitude and support for the treatment.

      community Switch to Dut??

      in Finasteride/Dutasteride  10 upvotes 6 years ago
      Considering a switch from finasteride to dutasteride for hair loss treatment, and the use of minoxidil as a last resort due to its effects on hair texture.

      community 5-month finasteride - diffuse thinning update

      in Progress Pictures  26 upvotes 1 year ago
      The user shared a 5-month update on using finasteride, minoxidil, and ketoconazole shampoo for diffuse thinning, along with supplements like B-Vitamins, D-Vitamins, Iron, and Beta carotene. They noted improvement in hair condition and encouraged others to check previous posts for more information.

      community new way to activate stem cells to make hair grow

       45 upvotes 7 years ago
      Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.

      community The Breezula 539% headline is doing a lot of heavy lifting right now.

      in Research/Science  14 upvotes 1 month ago
      Breezula shows promising results for hair loss, with one trial showing a 539% improvement and another 168%, but lacks combination data with treatments like minoxidil or dutasteride. Its mechanism differs from finasteride, potentially offering fewer side effects by blocking receptors locally at the follicle.

      community 6 weeks on minox and dut, looks like some temple gains?

      in Progress Pictures  9 upvotes 2 years ago
      The conversation is about a person's 6-week progress using 2.5 mg oral minoxidil, 0.5 mg dutasteride, weekly derma stamping at 1.5 mm, and rosemary oil for hair loss, with some initial shedding but no side effects. They are optimistic about future results.

      community Nest topical compound stack to fight hair loss

      in Treatment  1 upvotes 2 years ago
      The user is seeking advice for the best topical treatment to combat their ongoing hair loss, despite already using oral dutasteride, RU-58841, and minoxidil. They are considering adding CB-03-01 or topical Spiro to their regimen to lower testosterone levels at the follicles.

      community Will Pp405 be the Ozempic of bald Guys

      in Research/Science  101 upvotes 4 months ago
      PP405 is being discussed as a potential hair loss treatment, possibly more effective than minoxidil. There are concerns about its effectiveness and product contamination, but some users report early signs of hair regrowth.

      community Veradermics VDPHL01 Topline Results for Extended-Release Oral Minoxidil

      in Minoxidil  71 upvotes 1 month ago
      Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

      community minoxidil on eyebrows feedback

      in Female  4 upvotes 2 years ago
      A female user is seeking feedback on using topical minoxidil on eyebrows due to eyebrow loss, as oral minoxidil hasn't worked and they avoid Latisse due to potential fat loss.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 7 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.

      community Been diagnosed with telogen effluvium and MPB

      in Chat  3 upvotes 8 months ago
      A 21-year-old male diagnosed with telogen effluvium and male pattern baldness started oral finasteride, which initially slowed hair loss and slightly thickened hair, but experienced increased shedding after surgery. The doctor recommended iron and vitamin D supplements, and the user is seeking additional advice.

      community Maintaining hair until Breezula without Fin

      in Treatment  6 upvotes 5 years ago
      A 21-year-old male experienced side effects from topical finasteride and is seeking alternative treatments to maintain hair until Breezula is available. He is considering using minoxidil, Nizoral, micro-needling, and vitamin D supplementation, and may try CB or RU58841 if necessary.