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      community Breezula Phase 3 Results enough for maintenance?

      in Treatment  11 upvotes 1 month ago
      Breezula shows promise in stabilizing hair loss and potentially promoting regrowth at the one-year mark, offering hope for those who can't tolerate 5AR inhibitors. Its local targeting of androgen receptors could be a significant advancement if it avoids systemic side effects.

      community We need to create a Discord KX-826 Monotheray group:

      in Research/Science  29 upvotes 3 years ago
      The conversation is about starting a Discord group for people using KX-826 as their only treatment for hair loss, excluding those who are not serious or use multiple treatments. Someone agrees with the idea but mentions "GP :3," which is unclear.

      community A less common type of hairloss case

      in Research/Science  4 upvotes 2 months ago
      High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

      community Why I am not balding unlike my family?

      in General  71 upvotes 1 year ago
      The user is questioning why they are not experiencing hair loss like their family members. They are considering whether genetics or preventive treatments like Minoxidil, finasteride, or RU58841 might be influencing their hair retention.

      community Q1/Q2 Exciting times ahead - hope!

      in Research/Science  16 upvotes 1 year ago
      The conversation discusses various hair loss treatments, including Breezula, KX826, and PP405, with mixed opinions on their effectiveness compared to finasteride and minoxidil. Some users express skepticism about the new treatments, while others remain hopeful about future developments.

      community two months on 2-deoxy-d-ribose (2ddr)

      in Progress Pictures  10 upvotes 11 months ago
      The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

      community second shed on dutasteride, but a woman

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A woman experiencing hormonal hair loss is on dutasteride and bicalutamide, which initially improved her hair, but she is now experiencing a second shedding phase with significant short hair loss. Despite normal hormone levels and no deficiencies, she is unsure if this shedding is normal and seeks advice.

      community Should we give up on Breezula?

      in Research/Science  10 upvotes 6 months ago
      Breezula's potential as a hair loss treatment is debated, with some seeing promise despite delays, while others suggest alternatives like Pyrilutamide. Breezula is compared to topical finasteride, with hopes for a better side effect profile.

      community What are the chances of being chosen for PP405 trials?

      in Research/Science  3 upvotes 4 months ago
      The conversation discusses the potential benefits and risks of participating in the PP405 hair loss trials, emphasizing that those using Minoxidil or finasteride are less likely to be accepted. Participants are interested in the trial as it offers hope for effective treatment without the side effects associated with current medications.

      community Treatment of Male Pattern Baldness with Botulinum Toxin

      in Treatment  12 upvotes 7 years ago
      The conversation discusses using Botox to treat male pattern baldness, suggesting it may promote hair growth by increasing scalp blood flow and oxygen, reducing dihydrotestosterone levels. The user wonders why this treatment is not widely discussed or if it has been discredited.

      community GT20029 Anageninc Market Availability

      in Research/Science  166 upvotes 3 years ago
      The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.

      community Bicalutamide effect on androgens?

      in Treatment  4 upvotes 5 years ago
      Bicalutamide blocks androgen receptors, preventing testosterone and DHT from binding, which can help with hair loss but may cause feminization. It is not recommended for those who do not want feminization effects.

      community 2-Deoxy-D-Ribose official Product

      in Research/Science  6 upvotes 1 year ago
      2-Deoxy-D-Ribose is discussed as a potential hair loss treatment, but skepticism exists due to lack of human testing. The original poster uses a combination of topical Minoxidil, oral Finasteride, topical RU58841, and other treatments, reporting some hair regrowth but not significant results.

      community PP405 (Non) Update - Feb 2025

      in Research/Science  34 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community How to overcome baldness with finasteride allergy

      in Chat  5 upvotes 2 months ago
      The conversation discusses alternatives for hair loss treatment for someone allergic to finasteride, suggesting options like hair systems, topical anti-androgens such as CB-03-01, RU58841, and kx-826. It highlights the challenges faced by individuals allergic to anti-androgen inhibitors and the need for more information on this topic.

      community What has the evidence been on side effects with CB?

      in Research/Science  4 upvotes 5 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.