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community A concern regarding the upcoming androgen degrader drug GT20029

in Chat 11 upvotes 1 year ago

GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 133 upvotes 2 years ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community 1 year progress update, dut+min

in Progress Pictures 160 upvotes 1 month ago

A 35-year-old shared their 1-year hair loss treatment progress using 0.5mg Dutasteride, 5mg oral Minoxidil, topical Minoxidil, and Ducray Anaphase+ shampoo daily, noting significant changes after 4 months despite some shedding. They reported minor side effects and followed their dermatologist's advice for the treatment plan.

community HMI 115 Phase 2 - Leaked pics from Discord

in Research/Science 362 upvotes 2 years ago

The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

community Kintor Pharmaceutical Announced U.S. FDA Has Greenlighted Phase II Clinical Trial for Pyrilutamide to Treat Androgenetic Alopecia

in Treatment 26 upvotes 4 years ago

Chinese company gets green light for Pyrilutamide Phase II trial for androgenetic alopecia. Androgen receptors downregulate in androgen deficient environments.

community Thinking of getting transplant to refill density lost from traction alopecia

in Transplants 16 upvotes 2 years ago

A 22-year-old with 4c hair is considering a hair transplant to address traction alopecia caused by braid extensions. They have tried derma stamping, oils, and minoxidil but stopped due to side effects.

community Tip for diffuse thinners- reverse washing

in Styling 68 upvotes 1 year ago

Reverse conditioning can help achieve volume and well-conditioned hair for those with diffuse thinning. The user also mentioned using dutasteride.

community Women complaining of bad effects from Winlevi (Clascoterone 1%)

in Treatment 11 upvotes 6 months ago

Women experienced severe reactions, including Topical Steroid Withdrawal (TSW), from using Winlevi (Clascoterone 1%) on their faces. Concerns were raised about the potential risks of higher concentrations, especially for hair loss treatment.

community [34M] Diffuse Loss Progress: Dut/Oral & Topical Min/Keto/Microneedling

in Progress Pictures 129 upvotes 8 months ago

A 34-year-old man with diffuse hair loss experienced regrowth and hair thickening using daily Dutasteride, oral and topical Minoxidil, a specialized shampoo, and microneedling. He switched from Finasteride to Dutasteride after seeing significant improvement in a peer, reporting no side effects.

community Switching from oral to topical dut

in Finasteride/Dutasteride 1 upvotes 4 months ago

Switching from oral to topical dutasteride can cause shedding due to changes in DHT levels, and it's recommended to overlap both treatments to minimize this effect. Topical dutasteride may cause scalp irritation, and the user is considering dutasteride mesotherapy as an alternative.

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