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      community The Big Fat Layer II

      in Research/Science  26 upvotes 5 years ago
      Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  250 upvotes 3 years ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.

      community Stacking Fluridil / Topilutamide with other + aqueous topicals?

      in Technology  1 upvotes 1 year ago
      The conversation discusses how to use fluridil/topilutamide with other hair loss treatments like liquid minoxidil and CB-03-01, considering fluridil's hydrophobic nature and potential degradation with water. The user questions the necessity of washing hair only once per week as suggested by the manufacturer.

      community Does anybody have good results with ghk cu or ahk cu?

      in Treatment  7 upvotes 1 month ago
      GHK-Cu and AHK-Cu peptides show limited success for hair loss, with skepticism about their effectiveness and concerns about misleading claims. Users report better results when combined with treatments like finasteride, dutasteride, minoxidil, and other methods.

      community 11 years on only fin, it can work! 19yo - 30yo

      in Progress Pictures  212 upvotes 2 years ago
      A user shared progress pictures showing improvement in hair thickness over 11 years using only finasteride, taken three times a week, with no side effects. Commenters reacted positively, with one wishing they had started treatment earlier.

      community Pp405 full presentation on new topical

      in Product  105 upvotes 2 months ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.

      community Nizoral, Alpecin, Nioxin, Biolage, Viviscal. Shampoos

      in Product  10 upvotes 2 years ago
      The user tried various shampoos for thinning hair without clear results, except for Viviscal which noticeably thickened their hair. They noted that no shampoo can regrow hair and provided links to YouTube reviews for further information.

      community How long are Pelage going to milk the phase 2a results of PP405?

      in Chat  21 upvotes 4 months ago
      PP405, a potential hair loss treatment, is facing delays in releasing Phase 2 results, causing frustration among users who compare it to past failed treatments. Despite skepticism, some remain hopeful about PP405's future, while others discuss alternative treatments like Clascoterone and its expected market release.

      community Koshine826 - LX-826? machine translation of the news article

      in Product  5 upvotes 1 year ago
      KOSHINE826 is a new anti-hair loss and hair growth solution that claims to effectively control oil, reduce hair fall, and promote real hair growth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinical trials.

      community The amazing fast pace of PP405.

      in Chat  327 upvotes 7 months ago
      PP405 is a new hair loss treatment advancing quickly in trials, generating excitement and skepticism about its effectiveness and marketing claims. Some see it as a potential alternative to minoxidil and finasteride, but concerns about long-term effects and the need for DHT blockers persist.

      community pictures before I started pyrilutamide (repost)

      in Progress Pictures  124 upvotes 3 years ago
      Automatic-Law-3612's progress with hair loss treatments, including topical finasteride, topical dutasteride, minoxidil and pyrilutamide. They have been using these products for two weeks and noticed baby hairs in their temples getting longer.

      community 2+ years of KX826, Not confident

      in Treatment  7 upvotes 1 month ago
      The conversation discusses the use of KX826 for hair loss, with mixed opinions on its effectiveness. Some users are skeptical, mentioning no significant progress or regrowth, and others suggest it might be a scam or that data may be manipulated.

      community 6 months on the sauce- Min,Fin,DR

      in Progress Pictures  633 upvotes 3 years ago
      A user's successful 6-month journey with Minoxidil, Finasteride and 0.05 Derma Rolling to regain their hairline, eyebrows, facial hair and overall youthful look. They also discussed the use of topical minoxidil for eyebrow thickening, as well as other skincare routines and healthy lifestyle habits.

      community Why are there no proper phase 3 trials for RU

      in Chat  4 upvotes 2 months ago
      RU58841 lacks FDA approval due to financial and safety concerns, including potential cardiological side effects. The company abandoned further research, and users report adverse effects like heart palpitations and gynecomastia.

      community 11 month Progress 17-18yo with RU58841*

      in Progress Pictures  49 upvotes 1 year ago
      The user experienced hair regrowth using a combination of Minoxidil, Finasteride, and RU58841, with Minoxidil used initially and the other treatments added later. The user believes the combination of Finasteride and RU58841 contributed to the regrowth, with RU sourced from MVsupplement.

      community 40 days on topical fin+min + kx-826

      in Progress Pictures  22 upvotes 2 months ago
      A user shared progress pictures after 40 days of using topical finasteride, minoxidil, and KX-826 following a hair transplant. They previously used Polaris NR-11, which contains finasteride and minoxidil, and experienced significant hair regrowth.

      community Pp405 phase 2a clinical results

      in Research/Science  40 upvotes 11 months ago
      PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.

      community Clascoterone (Winlevi) Update for Canada

      in Treatment  15 upvotes 3 years ago
      Clascoterone cream was submitted for review to Health Canada in August 2022, with hopes of approval within 3-6 months. It may potentially enhance finasteride's effects for hair loss treatment.

      community important questions about RU58841

      in Research/Science  3 upvotes 2 years ago
      The user has been using finasteride for hair loss and is considering adding RU58841. They ask about RU58841's effectiveness, potential heart side effects, duration of action, dosage increase over time, transitioning to GT20029, and where to find the liquid form.