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community FCE 28260: A Forgotten 5α-Reductase Inhibitor

in Research 330 upvotes 1 year ago

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

community 3 hair transplants | 11,102 grafts | 28 yrs old | NW 6/7

in Transplants 149 upvotes 1 year ago

A 28-year-old underwent three hair transplants totaling 11,102 grafts at Eugenix, using finasteride and minoxidil to manage advanced hair loss. Despite limited density, the results are satisfactory, allowing the individual to feel presentable without a hat.

community What’s the appropriate dose of oral Min for a beginner?

in Minoxidil 89 upvotes 1 year ago

A 23-year-old is using oral minoxidil (1.25 mg) and finasteride (1 mg) for hair loss, with additional weekly dermarolling. They are considering whether to increase the minoxidil dose to 2.5 mg but are advised to stay at 1.25 mg for now.

community Homebrewing RU58841 as a gear user

in Product 6 upvotes 3 weeks ago

The conversation discusses using RU58841, Minoxidil, and finasteride for hair loss treatment. It focuses on homebrewing RU58841 while using other treatments.

community I’m back boys there is hope! Fin/min 1/2mg oral 5% topical (when I remember) micro needle fortnightly nizoral 2 x a week

in Progress Pictures 131 upvotes 3 years ago

A user's progress with hair loss treatment, which includes taking 1/2mg of Fin/Min orally daily and using 5% topical Minoxidil in the evenings; additionally, micro-needling is performed fortnightly, along with 2 Nizoral washes per week.

community RU55841 premixed solution vs powder

in Treatment 4 upvotes 5 years ago

RU58841 treatment for hair loss, comparing premixed solutions to powder form. Users prefer powder for cost-effectiveness and customization.

community When do you guys apply wax and sunscreen to your hair and scalp after minoxidil in the morning?

in Minoxidil 67 upvotes 9 months ago

Apply wax and sunscreen at least 30 minutes after minoxidil to ensure effectiveness. Avoid showering or exercising for 4 hours post-application.

community Can I mix the Premixed RU58841 Solution into Alfatradiol?

in Treatment 4 upvotes 1 year ago

The user wants to mix 0.2 ml of RU58841 solution with 2 ml of Alfatradiol to use 10 mg of RU58841 daily due to concerns about side effects. They are asking if this combination would be effective for hair loss treatment.

community (33 M) 7 weeks Topical fin + Min, ru, keto, derma stamp results

in Progress Pictures 116 upvotes 2 years ago

The user "natiggiz" shared their early progress in filling in bald patches using topical finasteride, minoxidil, RU58841, ketoconazole, and derma stamp. Other users commented on the great results and expressed jealousy.

community Fin 1mg Topical Minoxidil 5% 3 months

in Is this regrowth? 43 upvotes 5 months ago

A 30-year-old is using oral finasteride 1mg daily, topical minoxidil 5% twice a day, dermastamping, Nizoral shampoo, and supplements for hair regrowth. They report positive results and plan to update with longer hair in the future.

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