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      community Beating gyno symptoms on fin: my recent success

      in Update  18 upvotes 4 years ago
      A user successfully managed finasteride-induced gyno symptoms by making lifestyle changes, including fasting, avoiding soy, and increasing cardio. They resumed finasteride with a lower dose combined with minoxidil and P7 vitamins without recurrence of symptoms.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 3 months ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community Just started DualGen-15 Plus ( w/Finasteride )

      in Finasteride  11 upvotes 7 years ago
      A user discusses their hair loss journey, starting with 5% minoxidil and nizoral, and now using DualGen-15 Plus with 15% minoxidil and 0.1% finasteride. They also use biotin, pumpkin seed oil, Pura D'or Professional shampoo, and derma rolling, noting some shedding and side effects.

      community When will GT20029 become available for group buy?

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses the potential availability of GT20029 for hair loss treatment, with one user noting promising Phase 1 results and inquiring about gray market access. Another user humorously suggests it will take 50 years to become available.

      community ultimate nuclear stack? need more suggestions bruhh

      in Technology  2 upvotes 10 months ago
      The conversation discusses an extensive hair loss treatment regimen including dutasteride, GT20029, RU58841, pyrilutamide, minoxidil, microneedling, ketoconazole shampoo, and experimental compounds. The user humorously describes their approach as a comprehensive strategy to combat hair loss while maintaining hair growth.

      community A concern regarding the upcoming androgen degrader drug GT20029

      in Chat  11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community I ingested RU58841 orally to see if its legit

      in Chat  136 upvotes 1 year ago
      A user ingested RU58841 orally and experienced severe heart and breathing issues, requiring emergency medical assistance. They concluded that MV supplements is a legitimate supplier but warned of the serious side effects.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  8 upvotes 11 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Donald Glover’s (aka Childish Gambino) seamless hair transplant results

      in Transplants 3 years ago
      Donald Glover's (aka Childish Gambino) hair transplant results, which appear to be moderate with around 1000 grafts. Various users discuss the previous and current appearance of his hairline and speculate that he may have used medications like Minoxidil or finasteride to stabilize before getting a transplant.

      community An *insane* RU58841 success story

      in Progress Pictures  95 upvotes 1 year ago
      RU58841, oral and topical minoxidil, finasteride, and ketoconazole shampoo led to significant hair regrowth, though some suspect a hair transplant. Concerns about RU58841's side effects, like anxiety and heart issues, were discussed.

      community Is there any new drug that looks promising ?

      in Research/Science  26 upvotes 2 years ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Where is GT20029 already? Grrrr

      in Research/Science  20 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Brutal... RU58841 , is that true ?

      in Update  162 upvotes 1 year ago
      The conversation discusses hair loss treatments, specifically Minoxidil, finasteride, and RU58841. Concerns are raised about the lack of studies on RU58841 and its potential effects.

      community rudirect ru58841 seems bunk to me

      in Treatment  6 upvotes 1 month ago
      RU58841 from rudirect caused more hair shedding and itch, while anageninc's RU58841 improved the situation. Users are concerned about the quality and authenticity of RU58841 from different suppliers, including those from China.
      TresslessGPT is now available for free

      community TresslessGPT is now available for free

      in General  386 upvotes 2 years ago
      Tressless GPT is now free and accessible for hair loss advice. Treatments discussed include Minoxidil, finasteride, RU58841, dutasteride mesotherapy, topical melatonin, microneedling, and rapamycin.

      community Anyone know how to get second gen NSAA in the uk.

      in Transgender  1 upvotes 8 months ago
      A transwoman is struggling with hair loss despite using hormones, dutasteride, and Abiraterone, and is considering making her own treatments due to difficulty accessing them. She has also tried Eucapil and regularly uses Nizoral shampoo.

      community Oral Minoxidil - The Hyper-Responder Concept

      in Research/Science  5 upvotes 7 months ago
      Minoxidil's effectiveness varies due to genetic differences in the SULT1A1 enzyme, affecting how well it converts to its active form, minoxidil sulfate. Hyper-responders may experience rapid hair growth and increased side effects, such as pericardial effusion, even at low doses.

      community Is Maxogen-X from MinoxidilMax legit?

      in Treatment  1 upvotes 4 years ago
      The user is comparing the effectiveness of Maxogen-X and Happy Head topical products for treating hair loss. They note that Maxogen-X causes less flaking and dryness but are concerned about its absorption and overall effectiveness compared to Happy Head.

      community Extreme growth from only vitamins!

      in Update  63 upvotes 1 year ago
      A user experienced significant hair regrowth after improving their diet, getting sunlight, taking a multivitamin, and exercising, following a period of extreme calorie restriction and hair shedding. Others in the conversation attribute the hair regrowth to increased calorie intake rather than just vitamins.