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      community ET-02 Now Recruiting in Texas for Phase 1

      in Research/Science  20 upvotes 1 year ago
      Eirion Therapeutics is recruiting for phase 1 of ET-02 in Texas, which showed promising hair growth results in non-clinical studies. ET-02 demonstrated significantly more hair growth compared to Minoxidil.

      community Koshine826 - LX-826? machine translation of the news article

      in Product  4 upvotes 1 year ago
      KOSHINE826 is a new anti-hair loss and hair growth solution that claims to effectively control oil, reduce hair fall, and promote real hair growth. It targets androgenetic alopecia by inhibiting DHT and has shown promising results in clinical trials.

      community GT20029 phase II results release date?

      in Research/Science  17 upvotes 2 years ago
      The conversation is about the anticipated release date of phase II results for a hair loss treatment called GT20029 and the cautious optimism surrounding it due to past disappointments with similar treatments. Users expect an update in the next few months.

      community Combining Microneedling with LLLT

      in Research/Science  14 upvotes 1 year ago
      Combining microneedling with Low Level Laser Therapy (LLLT) for hair growth, with discussions on device legitimacy and effectiveness. Alternatives like PEMF and the use of oral and topical treatments such as dutasteride, minoxidil, and finasteride are also considered.

      community Jxl069 (pp405 api) week 8 update

      in Progress Pictures  204 upvotes 7 months ago
      The user shared minimal results from using JXL-069 for hair loss, noting a slight lengthening of vellus hairs and plans to switch to a prodrug variant due to limited effectiveness. They also mentioned using finasteride and minoxidil, which have plateaued in results.

      community Debunking Androgenetic Theory (Hair Transplants)

      in Research/Science  25 upvotes 2 years ago
      The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 1 year ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

      community Has anyone tried latanoprost+microneedle?

      in Microneedling  2 upvotes 2 years ago
      Microneedling combined with latanoprost may convert vellus hairs to transitional or terminal hairs. The user suggests using oral minoxidil to increase vellus hair, then applying a high concentration of latanoprost with microneedling for conversion.

      community GT20029: How It Works for Hair Loss - Hair Loss “Cure”

      in Research/Science  36 upvotes 2 months ago
      GT20029 is a potential treatment for androgenetic alopecia, addressing the root cause by targeting androgen receptors, unlike Minoxidil or Finasteride. It is seen as a preventative measure rather than a regrowth agent, with hopes for market release soon.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 5 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.

      community Welp - pp405 conference showed nothing

      in Update  79 upvotes 2 weeks ago
      PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

      community NW5 at 19. How many grafts do I need?

      in Transplants  142 upvotes 2 years ago
      A 19-year-old with rapid hair loss since 16 is considering a hair transplant but refuses to take finasteride or any 5α-Reductase inhibitors. They are currently using minoxidil, tretinoin, and microneedling with a Derminator 2, and only want hair until age 27.

      community 35% regrowth brothers and sisters! More effective than Minox and Fin?

      in Treatment  107 upvotes 7 years ago
      A double-blind clinical study that found ingestion of tocotrienols resulted in a 34.5% increase in hair regrowth compared to the placebo group, and discussion about potential side effects and cost of supplementation with vitamin E pills. The conversation noted that it may be more effective than commonly used treatments like minoxidil and finasteride.

      community Chances GT20029 releases by 2028?

      in Technology  7 upvotes 2 years ago
      The conversation is about hair loss treatments, specifically the anticipation for the release of a new treatment, GT20029, by 2028. Users are discussing their experiences with current treatments like finasteride and dutasteride, and the potential of future treatments, including FAK inhibitors and verteporfin trials.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community Forgotten Hair Loss Peptide by L'Oreal: KPV

      in Research/Science  5 upvotes 1 year ago
      KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.

      community Will vellus hairs in thinning areas go terminal if you go all out?

      in Transgender  9 upvotes 2 years ago
      A trans woman is using finasteride, minoxidil, microneedling, and HRT to address hair loss, with noticeable improvement in hairline shape and presence of vellus hairs. She is considering hair transplants if these treatments don't yield desired results within a year or two.