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      community Pyrilutamide / KX-826 / Koshine — has it been working for you?

      in Treatment  10 upvotes 1 year ago
      Pyrilutamide/KX-826 is being discussed for its effectiveness in hair regrowth, with some users reporting positive results, especially in early hair loss cases. Users have combined it with treatments like Minoxidil, and some experienced initial shedding before seeing regrowth.

      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

      community Is this finally regrowth at my temples?!

      in Is this regrowth?  16 upvotes 7 months ago
      The user switched from topical to oral finasteride and minoxidil, noticing thicker and longer baby hairs, suggesting potential regrowth at the temples. Other users agree it looks like a sign of success.

      community Great news recently for people with hairloss!

      in Research/Science  113 upvotes 1 year ago
      A potential treatment for alopecia involving a protein that calms hair follicles has shown promise in rats, but skepticism remains about its applicability to humans. Many users express doubt about the timeline for effective hair loss treatments, comparing it to past unfulfilled promises.

      community The story of RU58841/PSK3841

      in Research/Science 1 year ago
      RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

      community IGE Hair Loss and Miniaturization

      in Chat  3 upvotes 1 year ago
      A 23-year-old male is experiencing diffuse hair loss and miniaturization, possibly due to high IGE levels after using tofacitinib. He seeks advice and has not yet consulted a dermatologist.

      community Regenera & Exosomes – Do They Actually Work?

      in Treatment  7 upvotes 1 year ago
      Regenera Activa and exosome therapy are discussed for hair loss treatment, focusing on their effectiveness for regrowth, thickening, or reducing shedding. Users are seeking experiences and results from these treatments.

      community 10 months progression (plz respond)

      in Is this regrowth?  4 upvotes 2 months ago
      The user is experiencing hair shedding after using minoxidil and is considering switching to dutasteride while planning to increase their oral minoxidil dose. They also use nicotine pouches, Vyvanse, and GHK-Cu, and have noticed thicker eyebrows and lashes from oral minoxidil.

      community 1.5 years on dutasteride and on and off microneedling

      in Is this regrowth?  60 upvotes 1 year ago
      The user experienced hair regrowth using dutasteride daily, microneedling weekly, and Nizoral shampoo, after stopping minoxidil due to side effects. They also use a mix of pumpkin seed, rosemary, and peppermint oil, and are considering RU58841 for more temple area thickness.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 10 months ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community Finasteride influence on other hormones

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

      community Pyrilutamide Trial Phase 3 Results?

      in Research/Science  10 upvotes 2 years ago
      The conversation is about the release of Phase 3 trial results for pyrilutamide in China for treating hair loss. The user is inquiring if the actual results have been posted, noting that a recent release did not contain them.

      community Bryan Johnson’s Hairloss Regimine

      in Research/Science  25 upvotes 3 years ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.

      community Why Is No One Talking About Chromosome 20?

      in Chat  32 upvotes 9 months ago
      Some hair loss may be linked to chromosome 20, which isn't affected by DHT blockers like finasteride. Treatments like minoxidil, microneedling, and genetic testing are suggested, but their effectiveness for this type of hair loss is uncertain.

      community Rethinking DHT and Hair Loss: Are We Targeting the Wrong Enemy?

      in Research/Science 1 year ago
      Blocking DHT is not a cure for hair loss; instead, altering how scalp follicles respond to DHT might be more effective. Current treatments like topical finasteride and minoxidil are temporary solutions, and future approaches may involve gene therapy and bioengineering to change follicle behavior.

      community Additional supplements / peptides to maximize finasteride benefit

      in Research/Science  3 upvotes 1 month ago
      The user is using finasteride, HGH, GHK-CU, BPC-157, KPV, biotin/collagen/keratin vitamins, ketoconazole shampoo, and low-dose naltrexone to address hair loss, avoiding minoxidil due to past shedding experiences. Adenosine is discussed as a potential alternative to minoxidil, though it is noted to be expensive and hard to find.

      community Has anyone got results from pyrilutamide?

      in Research/Science  3 upvotes 6 months ago
      The user maintained hair with minoxidil, alfatradiol, and fluridil after stopping finasteride due to erectile dysfunction. They recently added pyrilutamide and are seeking feedback on its effectiveness after six months of use.

      community 11 months progress, HRT + Fin + Min

      in Progress Pictures  366 upvotes 3 months ago
      A transwoman shared her 11-month progress using hormone replacement therapy (HRT), finasteride, and minoxidil, reporting significant hair regrowth and satisfaction with the results. The discussion included various perspectives on HRT, its effects on hair and sexual function, and personal experiences with similar treatments.

      community Has anyone had luck with low-level laser therapy (LLLT) devices?

      in Question  5 upvotes 8 years ago
      Low-level laser therapy (LLLT) devices may help thicken existing hair but are not effective for regrowing hair on bald areas. Users suggest sticking with finasteride, minoxidil, and dermapenning, as LLLT devices like Capillus are expensive and results are mixed.

      community About Pyrilutamide Phase II US Trial

      in Research/Science  11 upvotes 2 years ago
      The conversation discusses the comparison of Pyrilutamide Phase II US trial results with 1 mg finasteride for hair loss treatment. It mentions that the total hair count increase in the US trial was not as good as the China trial.