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A 31-year-old female stopped excessive hair shedding using Nizoral shampoo, diluted apple cider vinegar rinse, daily scalp massages, and oral iron and biotin supplements. She noticed a significant reduction in hair loss after 2.5 months and is observing potential regrowth.

A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

The user experienced significant hair shedding after using a dermapen at 1.5mm weekly, which they later realized was too much. They are now using a dermapen at 0.75mm weekly and are also using topical minoxidil twice daily and finasteride 1.25mg daily.

User started hair loss treatment in November 2020 using Finasteride, Minoxidil, Dermaroller, castor oil, Nizoral, and supplements. They experienced improvements but had a second shed in February and seek feedback on their routine.

The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

A user stopped using finasteride and switched to a mix of essential oils in jojoba oil to treat hair loss, which reduced itching and hair shedding significantly. They shared their experience, noting that dermatologists were not helpful.

A user shared their progress in hair regrowth after 3 months using Minoxidil, Finasteride, Biotin, and dermarolling, feeling confident enough to go outside without a hat for the first time in 2 years. The conversation includes questions about side effects, dermarolling, and hair care products.

Hair loss treatments discussed include promising Pyr available online and Verteporfin dosing after FUE for follicle regeneration, but no updates on SCUBE3.

A user's 2.5 year hair loss progress with Minoxidil, dermarolling, and Nizoral treatments, as well as taking biotin and a multivitamin supplement, with the intention of trying DIY topical finasteride in the future.

The user stopped using oral minoxidil due to shedding and is continuing with oral finasteride and hair vitamins. They are advised that shedding is temporary and to maintain finasteride use, with examples of others successfully managing hair loss with similar treatments.

The user started treating hair loss with minoxidil, Nizoral shampoo, dermarolling, and castor oil, and noticed small hairs growing at the temples. They plan to add biotin and azelaic acid to their routine but are avoiding finasteride due to potential side effects.

The user experienced significant hair regrowth using a regimen of minoxidil 5% twice daily, finasteride 1 mg daily, microneedling, ketoconazole 2% twice a week, and occasional castor and coconut oil, along with daily scalp massages. They are optimistic about reversing their Norwood 5/6 hair loss.

A 32-year-old woman reported significant hair regrowth after 103 days of using 5% minoxidil once daily, along with biotin, iron supplements, and a balanced diet. She observed many new baby hairs and no bald spots, aiming for denser and longer hair while maintaining her regimen.

A user shared their progress using liquid minoxidil for hair regrowth and plans to switch to foam minoxidil due to flaking. They asked if the foam version would maintain their results and mentioned considering adding finasteride and a derma pen soon.

LemonyBonobo started oral minoxidil a week ago, experiencing significant shedding, and is concerned about potentially worsening their hair condition. They also use dutasteride, topical minoxidil, and dermarolling. Elyktronix, who has been on oral minoxidil for 15 months, recommends it, noting that shedding can be a positive response and that results take time.

A user shared progress pictures after three months of using topical minoxidil for hair loss, planning to add dermarolling later. Some responders are skeptical of the rapid hair growth, while others are impressed or question the authenticity of the photos.

Switching from topical to oral minoxidil may cause initial hair shedding, but oral minoxidil is likely more effective. Shedding should be temporary, and results should be monitored over a few months.

Pelage PP405 is a new hair loss treatment in trials, potentially reactivating dormant hair follicles without affecting hormones. Results are expected in February 2025, offering an alternative to minoxidil and finasteride.

A 36-year-old man restarted hair loss treatment after a break, using topical Minoxidil 5% twice daily, topical Finasteride 0.01% daily, and Ketoconazole 2% three times a week, along with supplements like Vitamin B12, D3, C, Biotin, Omega-3, zinc, and copper. He avoids oral Finasteride due to side effects and plans to evaluate progress after a year.

The user switched from finasteride from Ro to Amazon pharmacy and noticed increased hair shedding and thinning, questioning if it's normal shedding or if they need to adjust their treatment. They have been using finasteride and topical minoxidil for 6-7 months without seeing regrowth or shedding initially.

The user is considering switching between topical minoxidil (10%) and oral minoxidil (2.5mg) to manage hair shedding around the temples, while also using a dermaroller and biotin. They are concerned about the potential side effects of oral minoxidil, such as hypertrichosis, and the impact on hair shedding if they stop using it.

The user used minoxidil unnecessarily for two months due to a perceived hair loss but realized their hairline hadn't changed in 2.5 years. They are concerned about shedding caused by minoxidil and whether stopping its use will allow regrowth or cause permanent damage.

A user with aggressive male pattern baldness found that topical melatonin significantly reduced their hair shedding to 1 or 2 hairs per day and noticed some thickening of side hair. They tried many treatments like finasteride and minoxidil with little success, but topical melatonin showed immediate results in reducing hair loss.

The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

The post discusses the completion of the HMI-115 Australian Phase 1 Trial for hair loss treatment. The user speculates about the potential early release of the trial results.

OP mixed RU58841 with minoxidil and noticed undissolved particles. They are seeking advice on whether it matters or how to fully dissolve it.

The conversation discusses hair loss, with users suggesting treatments like ketoconazole shampoo, finasteride, and dutasteride. Symptoms like burning and tenderness are mentioned, with recommendations to see a dermatologist for potential scarring alopecia.

A female user experienced hair loss after Covid and used Minoxidil 5% but saw more hair loss over time. She also uses alfatradiol, topical MSM, and betamethasone sporadically, and is unsure if Minoxidil is beneficial.

Hair regrowth progress using finasteride, minoxidil, and dermarolling. Visible improvements started around month 6, with initial shedding from minoxidil.

Matt-3422 shared his hair loss treatment journey, starting with great results from Minoxidil and oral Finasteride, then switching to RU58841 and topical Finasteride due to worsening hair loss. He's experiencing scalp irritation and is unsure if he should continue with his current regimen, while others suggest scalp care and alternative treatments.