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420-450 / 1000+ resultscommunity Preparing Topical Finasteride with Stemoxydine
Creating a topical solution combining finasteride and stemoxydine to treat hair loss, and the discussion of whether 15mg of finasteride would be sufficient for 60ml solvent.
community Sea salt spray for thin, oily hair
Sea salt spray is recommended for adding volume and managing oily, thin hair. It's affordable and effective, with store brands being a good option.
community PP405 Identity Research
PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.
community How cyproterone acetate and spironolactone come to my mind whenever I look in the mirror
The conversation humorously discusses hair loss treatments, mentioning spironolactone and cyproterone acetate. It reflects a sense of frustration and satire about the effectiveness of these treatments.
community Regimen update - Added oral Minox and RU
The user updated their hair loss treatment to include daily dutasteride, oral minoxidil, topical dutasteride with minoxidil and tretinoin, and RU58841. Commenters feel the extensive treatment is unnecessary for the user's level of hair loss.
community Just me or has oral minoxidil rose in popularity over the past few years?
Oral minoxidil has gained popularity as a hair loss treatment, with more online discussions and research showing it's safe in low doses. A viral New York Times article also contributed to its increased acceptance.
community thoughts on this approach to topical fin that I want to try?
User plans to switch from oral to .005% topical finasteride, using a solvent from minoxidilmax and later Essengen-F. They will monitor DHT levels and seek advice on solvents and sleep caps.
community Extreme caution: my experience using Ru58841 only once
An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.
community New molecule PP405 vs exercise
PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.
community RU58841 and impact onmale fertility?
The conversation is about the potential impact of RU58841 on male fertility, specifically regarding sperm concentration, total count, and motility. The user is curious about the likelihood of RU58841 reducing fertility based on its mechanism of action and comparisons to similar substances.
community Any UK sources for minoxidil+RU58841 solution together? That doesn’t contain PG?
A user is seeking a UK source for a combined minoxidil and RU58841 solution that doesn't contain scalp-irritating ingredients. They specifically want a product without propylene glycol (PG).
community 51M - 1mg Oral Fin daily, 5% topical min twice daily, dermarolling 0.3mm daily/1mm weekly, Nizoral twice a week. Photos are 2 months apart
A 51-year-old man uses 1mg oral finasteride daily, 5% topical minoxidil twice daily, dermarolling, and Nizoral twice a week for hair regrowth. He shows significant progress after two months and is happy with the improvement.
community Under-eye wrinkle appeared after 4 weeks of oral minoxidil use, along with significant dark circles and under-eye puffiness.
The user's experience with oral minoxidil, which resulted in under-eye wrinkles; other users sharing their experiences and advice regarding hair loss treatments such as topical minoxidil, finasteride, RU58841, and collagen supplementation.
community Topical fin (0.008%) + min - left: 26yo, right: 30yo, goodbye MBP, I keep my NW-0 :D
A user shared progress pictures showing successful hair retention using a low-dose topical finasteride (0.008%) combined with minoxidil. Users discussed the effectiveness of the treatment, minimal effective dosing, and avoiding systemic side effects.
community Homemade topical spironolactone
The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.
community PP405 2a study was a safety study. Some rational explaining.
The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.
community Cassiopea Announces Very Positive Interim Analysis Phase 2 Results for Breezula® (Clascoterone) in Treating Androgenetic Alopecia
Breezula® (Clascoterone) showed promising results in a Phase 2 trial for treating hair loss, being as effective as Propecia with no serious side effects. It might be released between 2021-2022, and a related acne treatment with the same active ingredient could be used in the meantime.
community Topical Dutasteride 1% - High dosage?
User asks about two topical dutasteride solutions and wonders if 1% concentration is overkill compared to 0.1%. They also consider trying standard topical dutasteride before using Minoxidil.
community Starting 5mg oral min after being on 2.5mg since February
The user is increasing their oral minoxidil dosage from 2.5mg to 5mg after using 1mg finasteride and topical minoxidil foam for over three years without desired results. They have also been microneedling and using tretinoin cream, recently increasing the tretinoin dosage to 0.1%.
community (large post) Ambitious, "natural" treatment regime, suggestions thoughts or trolls welcome
The post discusses a hair loss treatment regime using Nizoral, a laser helmet, dermaroller, bentonite clay mask with essential oils, and ketoconazole shampoo. The user avoids finasteride and minoxidil due to concerns about side effects and pet safety.
community Is anyone taking both boron and p5p to lower SHBG and Prolactin respectively? What are you experience on this?
The user is applying topical finasteride with stemoxydine for hair loss and has noticed hair thickening but no regrowth after two months. They also report high SHBG and prolactin levels and a lack of morning erections, even on low doses of medication.
community New article on PP405..........
Scientists at UCLA have developed a promising treatment for male pattern baldness using a molecule called PP405, which can potentially stimulate dormant hair follicles. Initial trials showed significant results within a week, but larger clinical trials are needed to confirm its efficacy and safety.
community I'm about to order some retinol and azelaic acid from the ordinary
The conversation discusses using retinol to enhance minoxidil's effectiveness for hair loss, with a user considering The Ordinary's 0.5% retinol and seeking advice on azelaic acid concentration. Other users suggest using tretinoin instead and consider pre-formulated products combining minoxidil, tretinoin, and azelaic acid, but the original poster has not seen improvement from dermarolling.
community Alfatradiol as a base for Topical Finasteride
User creates 0.1% topical finasteride solution using Alfatradiol Avixis base. Seeks help to ensure alfatradiol base dissolves finasteride.
community Clascoterone ph3 results ready
Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.
community Compounding for topical formulations?
The post discusses the high cost of a topical hair loss treatment from Happy Head, which contains finasteride, minoxidil, retinoic acid, and hydrocortisone. The user is seeking cheaper alternatives, specifically asking if there are compounding pharmacies that can recreate the same or similar formulation.
community Tressless regrowth results megapost
The conversation is about organizing hair regrowth results using a standard format in a single post for easier access. Treatments mentioned include oral minoxidil, oral finasteride, and dermarolling.
community Visible results after 10 weeks, (M25), E-En+DHPA, bica, min
Visible hair improvement after 10 weeks using minoxidil, estradiol enanthate, acetophenide algestone, and bicalutamide. The user is a 25-year-old male with reduced testosterone levels, expressing a preference for less masculinity.
community KX-826 users: 0.5% vs 0.9% vs foam
KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.