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      community When will gt20029 come out???

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses the anticipated release of GT20029, with some users expressing skepticism about its availability. It also mentions the use of treatments like Minoxidil, finasteride, RU58841, and dutasteride for hair loss.

      community Updates about KX-826 & GT20029

      in Research/Science  16 upvotes 3 years ago
      The conversation discusses potential advancements in two hair loss drugs, KX-826 and GT20029, and the interest in whether transitioning from oral finasteride to these drugs would maintain hair growth. One reply expresses skepticism about the compounds' representation.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  7 upvotes 9 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Anyone immediately lose hope for gt20029 when they realised it’s developed by kintor

      in Research/Science  6 upvotes 3 months ago
      The conversation discusses various hair loss treatments, including minoxidil, finasteride, dutasteride, pyrilutamide, alfatrodial, and nizoral, with a focus on the potential of new treatments like gt20029 and breezula. There is optimism about novel treatments that don't have systemic effects, although skepticism remains about the effectiveness of some new drugs.

      community 90 days in - starting to get excited about these results!

      in Progress Pictures  404 upvotes 1 year ago
      The user is excited about hair regrowth results after using Hims topical finasteride and minoxidil since December, along with derma rolling twice a week. They report no side effects and apply minoxidil after derma rolling, with noticeable progress in hair density.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Actifolic RU58841 and others Scam?

      in Treatment  5 upvotes 3 years ago
      Actifolic's RU58841 and Pyri products are perceived as ineffective, with users reporting no side effects or improvements, suggesting possible quality issues. Users recommend alternative sources and emphasize the importance of timing when using RU58841 with Minoxidil.

      community 1 yr on fin, min & dermaroller

      in Progress Pictures  493 upvotes 4 years ago
      User Clay1211 shared 1-year progress using finasteride, minoxidil, and dermaroller for hair loss. Commenters expressed surprise and praised the impressive results.

      community AnagenInc says GT20029 is possible now

      in Research/Science  117 upvotes 3 years ago
      AnagenInc is ready to produce a hair loss treatment called GT20029 if there is enough demand. People are discussing combining it with other treatments like finasteride and minoxidil, and some are concerned about the legitimacy and safety of gray market products.

      community Anyone Taking CB-03-01

       7 upvotes 7 years ago
      The conversation is about someone seeking information on long-term users of CB-03-01 for hair loss, having experienced negative side effects from finasteride and facing rapid hair thinning.

      community Has anybody tried RU58841 and pyrilutamide together?

      in Chat  9 upvotes 8 months ago
      RU58841 and pyrilutamide are being discussed as potential hair loss treatments, with some users reporting side effects. There is interest in these treatments as alternatives to 5ar inhibitors and oral minoxidil due to concerns about safety and side effects.

      community Anyone get results with Ru58841?

      in Treatment  4 upvotes 1 month ago
      RU58841 stopped shedding after two weeks and improved hair after eight months. Initial thinning may occur within the first month.

      community ORAL MIN ,DERMAROLLING AND RU58841 PROGRESS 3 months (18,M)

      in Progress Pictures  80 upvotes 3 years ago
      The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.

      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       22 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community 5 month progress on Locklabs oral tablet

      in Progress Pictures  22 upvotes 3 months ago
      The user experienced significant hair regrowth over five months using Locklabs oral tablets, with no side effects and only a minor shed. They dye their hair black to cover natural blonde, which may affect perceived hair density.

      community One month Umbrella Labs PP405 results.

      in Progress Pictures  57 upvotes 4 months ago
      The user tried a product labeled as PP405 from Umbrella Labs for hair loss but saw no changes, and it was revealed to be a fake or misidentified product. The user is also using finasteride, minoxidil, and other treatments but is still experiencing hairline issues.

      community Group Buy for MR antagonist finerenone

      in Product  11 upvotes 2 years ago
      User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

      community Cmon Pyrilutamide and CosmeRNA 😭

      in Chat  36 upvotes 2 years ago
      Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.