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      community Side effects of topical azelaic acid?

      in Research/Science  5 upvotes 5 years ago
      Azelaic acid is considered a strong DHT inhibitor with no reported sexual side effects, making it a potential alternative for those who cannot use finasteride. It can be used with minoxidil, but may cause skin irritation.

      community Mintop Yuva 5 Review

      in Minoxidil  2 upvotes 5 years ago
      Dr. Reddy's Mintop Yuva 5 Minoxidil uses benzyl alcohol instead of ethyl alcohol or propylene glycol. The user is inquiring if this formulation causes dandruff or skin peeling and if its efficacy is affected.

      community Anagenic is trying to compound Gt20029

      in Treatment  56 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community Will Breezula simply be an overhyped flop?

      in Treatment  16 upvotes 5 months ago
      Breezula is seen as potentially overhyped, with concerns about its cost, effectiveness, and long-term benefits compared to existing treatments like finasteride and minoxidil. Some users believe it could complement existing treatments, while others are skeptical about its impact and prefer waiting for newer options like GT20029 and PP405.

      community Topical Pyrilutamide - Hormone Panel

      in Treatment  2 upvotes 2 years ago
      The user used 0.5 mL of 0.5 mg of Pyrilutamide for 60 days for hair loss, but didn't notice any hair growth. They shared their hormone panel results and are seeking advice on next steps.

      community Redensyl formula recommendation

      in Product  2 upvotes 1 year ago
      A user is seeking a hair loss formula containing Redensyl and Capixyl without caffeine, Saw Palmetto, or other herbs. They want recommendations for such a product.

      community Starting pyrilutamide boys wish me luck!

      in Treatment  36 upvotes 3 years ago
      A user beginning to take Pyrilutamide as a treatment for their hair loss, and other users sharing their experiences with the drug or similar treatments such as Minoxidil, Finasteride, and RU58841.

      community JXL082 is not PP405 and Everychem followed the wrong lead

      in Research/Science  43 upvotes 10 months ago
      JXL082 is not the same as PP405, leading to a halt in sales and a plan to synthesize the real PP405. There is skepticism about the safety and effectiveness of JXL082 and PP405, with concerns about patent issues and the long-term impact on hair growth.

      community Betamethasone dipropionate 0.05 (sernivo spray)

      in General  76 upvotes 1 year ago
      A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

      community Serenoa Repens (saw palmetto) + plus biotin

      in Chat  5 upvotes 3 years ago
      A user is using minoxidil for hair loss and considering adding finasteride but their dermatologist advised waiting to see if minoxidil works alone. They are thinking about taking saw palmetto (serenoa repens) and biotin as alternatives and are asking for others' experiences and potential side effects.

      community PP405 is NOT gray market jxl069

      in Technology  26 upvotes 4 months ago
      PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

      community Breezula hasn't even begun phase 3 trials yet. F*cking hell.

      in Treatment  44 upvotes 4 years ago
      The conversation is about the delay in Breezula's phase 3 trials and skepticism regarding its effectiveness compared to other treatments like RU58841 and Pyrilutamide. Some users prefer safety over effectiveness, while others express frustration with the slow progress and doubt Breezula will be a significant treatment for hair loss.

      community European release of clascoterone

      in Research/Science  13 upvotes 1 month ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community So Pyrilutamide has been postponed by one year. How likely is that to happen to GT20029

      in Treatment  27 upvotes 2 years ago
      The conversation discusses the delay in the release of a new hair loss treatment, Pyrilutamide, and speculates on potential safety concerns as a reason for the delay. It also mentions GT20029 as another future treatment option, with a release at least five years away, and touches on the avoidance of research chemicals due to uncertainty about their authenticity.

      community Can we try, collectively, a little zix experiment?

      in Treatment  7 upvotes 3 years ago
      User suggests a DIY zix formula for hair loss treatment and shares personal success with it. Another user disagrees, calling zix a "snake oil potion" and advises finding a real treatment instead.

      community Has anyone tried 2% Pyrilutamide from Anagenica?

      in Treatment  1 upvotes 1 year ago
      The conversation discusses using 2% Pyrilutamide from Anagenica for hair loss, as the user did not see results with 1% Pyrilutamide. The user is considering increasing the dosage but is concerned about the cost.

      community Forgotten Hair Loss Peptide by L'Oreal: KPV

      in Research/Science  4 upvotes 1 year ago
      KPV, a peptide patented by L'Oreal, may promote hair growth and reduce hair loss by extending the anagen phase and has anti-inflammatory properties. It could be combined with treatments like minoxidil for enhanced effects.

      community 5mg KX 826 Worked. Will 2.5mg Hold?

      in Technology  6 upvotes 1 year ago
      Reducing the dose of Pyrilutamide from 5mg to 2.5mg may still maintain hair loss results, but effectiveness can vary. Users discuss the cost and dosage implications, with some cautioning against reducing the dose due to its dose-dependent nature.

      community Rational Review of Pelage Results

      in Chat  11 upvotes 11 months ago
      A treatment showed a 20% hair density increase in weeks, with nearly a third of participants experiencing significant results, while questions remain about its long-term efficacy and effectiveness across different scalp areas. There is interest in combining it with finasteride and minoxidil for potentially better outcomes.

      community Breezula - what's the consensus?

      in Research/Science  7 upvotes 5 years ago
      People are discussing Breezula, a hair loss treatment, with mixed opinions on its value for the cost. Some are interested in it, while others think it's not worth the money.