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Did you mean Complete Androgen Insensitivity Syndrome?

GlossaryComplete Androgen Insensitivity Syndrome

genetic condition causing male individuals to develop female traits

Complete Androgen Insensitivity Syndrome (CAIS) is a genetic condition where an individual who is genetically male (with one X and one Y chromosome) is resistant to male hormones called androgens. As a result, the person has the physical traits of a female but does not have a uterus or ovaries, and typically has undescended testes. This condition is caused by mutations in the AR gene, which affects the body's ability to respond to androgens.

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research Sequence of the intron/exon junctions of the coding region of the human androgen receptor gene and identification of a point mutation in a family with complete androgen insensitivity.

32 citations , November 2020 in “UNC Libraries”

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

research A Novel Androgen Receptor Gene Mutation in a 46,XY Patient: Complete Androgen Insensitivity Syndrome

1 citations , August 2015 in “AACE Clinical Case Reports”

A new gene mutation causes complete androgen insensitivity in a 16-year-old with a female appearance.

research An adolescent girl presenting with primary amenorrhea: A case report of complete androgen insensitivity syndrome

October 2023 in “IJEM case reports”

A 15-year-old girl with no menstrual period was diagnosed with a genetic condition that makes her body unable to respond to male hormones, leading to female characteristics despite having male genetic makeup.

research SAT-213 Late Diagnosis of Complete Androgen Insensitivity

April 2019 in “Journal of the Endocrine Society”

A 31-year-old woman was diagnosed with Complete Androgen Insensitivity Syndrome much later than usual, leading to a call for earlier detection and treatment guidelines.

research A Case of Hair Regrowth in a Patient with Complete Androgen Insensitivity Syndrome and Female Pattern Hair Loss

January 2020 in “Journal of clinical and cosmetic dermatology”

A woman with hair loss regrew hair using minoxidil and spironolactone.

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community Fun thought experiment about halting hair loss permamently

in Research/Science 60 upvotes 2 years ago

A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

community My Theory Of Androgenic Alopecia

in Research/Science 20 upvotes 8 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

community How does dutasteride regrowth work?

in Finasteride/Dutasteride 7 upvotes 2 years ago

A 25-year-old man with hair loss from bleach damage is using oral minoxidil and considering adding Dutasteride for better regrowth and prevention. He seeks advice on Dutasteride's effectiveness and potential benefits over finasteride, and is also curious about RU58841.

community Can anyone confidently say their erections are the same on fin ?

in Chat 240 upvotes 2 years ago

The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

community Neck tension, and hair loss, I am 100 percent sure that there is a connection

in Treatment 19 upvotes 2 years ago

The user believes neck tension and poor posture contribute to hair loss, noticing improvements with yoga and muscle relaxation. Replies suggest androgenic alopecia as the cause and recommend exercises.

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