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research SRD5A3 Is Required for Converting Polyprenol to Dolichol and Is Mutated in a Congenital Glycosylation Disorder

260 citations , July 2010 in “Cell”

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

research Congenital Adrenal Hyperplasia: Current Insights in Pathophysiology, Diagnostics, and Management

188 citations , January 2022 in “PubMed”

Advancements in understanding, diagnosing, and managing congenital adrenal hyperplasia have improved treatment and long-term outcomes.

research The Hairless Gene Mutated in Congenital Hair Loss Disorders Encodes a Novel Nuclear Receptor Corepressor

178 citations , October 2001 in “Genes & Development”

The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.

research An Update on Congenital Adrenal Hyperplasia

151 citations , December 2004 in “Annals of the New York Academy of Sciences”

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

research Methimazole, Carbimazole, And Congenital Skin Defects

132 citations , January 1987 in “Annals of Internal Medicine”

Methimazole may cause skin defects in babies if taken during pregnancy.

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community REVOLUTION in AUGUST: New possibilities according to Dr. Muñoz (pinacidil, cromakalim, diazoxide and nicorandil)

in Technology 12 upvotes 3 months ago

Dr. Muñoz's discovery suggests that targeting potassium channels in fibroblasts could reactivate hair growth, offering new treatment possibilities for alopecia. Potential strategies include using minoxidil, diazoxide, and other potassium channel openers, as well as bioelectric devices and direct growth factor applications.

community Is this Better Than Topical Minoxidil? Topical Diazoxide

in Research/Science 6 upvotes 8 months ago

Topical diazoxide may be a promising hair regrowth treatment, especially for those who don't respond to minoxidil, as it activates potassium channels without needing sulfation. It appears safe for topical use, avoiding systemic effects seen in oral use.

community 31M. Just diagnosed with androgenic alopecia. Fears of min.

in Finasteride/Dutasteride 12 upvotes 3 months ago

A 31-year-old man with androgenic alopecia is considering treatments like finasteride, minoxidil, and ketoconazole shampoo but is worried about finasteride's side effects. Users recommend starting with finasteride or dutasteride for DHT blocking, suggesting topical solutions to reduce side effects.

community Questions on Minoxidil and Finasteride Efficacy After 10 Years of Hair Loss

in General 265 upvotes 5 months ago

Topical minoxidil with finasteride can help focus treatment on the scalp, with shedding being normal initially. Foam minoxidil is easier to apply, PRP's effectiveness varies, and anti-dandruff shampoos like ketoconazole are beneficial for scalp health.

community Boys,Thank you all. almost 90days into treatment. dut/minox/ketoconazole shampoo

in Progress Pictures 79 upvotes 1 year ago

The user is using oral dutasteride, topical minoxidil (Regaine foam 5%), and ketoconazole shampoo for hair loss, reporting good results with no significant side effects. The user is 26 years old and applies minoxidil once or twice daily.

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