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      Adverse Effects and Drug Interactions of Biologic Agents

      research Adverse Effects and Drug Interactions of Biologic Agents

      March 2010 in “Anti-inflammatory & anti-allergy agents in medicinal chemistry”
      Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.
      Sinus Node Dysfunction in a Child After Use of Topical Minoxidil

      research Sinus Node Dysfunction in a Child After Use of Topical Minoxidil

      1 citations , January 2018 in “Eastern Journal Of Medicine”
      This case report described a 9-year-old girl who developed sinus node dysfunction after using topical minoxidil for alopecia. Despite normal initial cardiac assessments, a 24-hour Holter monitor revealed asystolic attacks lasting 4 to 6 seconds, accompanied by syncope. The sinus node dysfunction was likely related to minoxidil, as assessed by the Naranjo adverse drug reaction probability tool. After discontinuing minoxidil, the patient's sinus node function normalized, and she was monitored without the need for a permanent pacemaker. The report highlighted the potential for serious cardiac side effects in pediatric patients using minoxidil, emphasizing the need for careful monitoring.

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