40 citations
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July 1981 in “Journal of Neuropathology & Experimental Neurology” Copper injections improved symptoms and prevented brain damage in brindled mice.
16 citations
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June 1983 in “Journal of Neurochemistry” Copper therapy improved health and enzyme activity in mice with copper deficiency.
December 2024 in “Pediatrics in Review” A 7-month-old boy with developmental delay and poor growth was diagnosed with Menkes disease, an X-linked recessive disorder characterized by copper deficiency, leading to neurodegeneration and distinctive hair changes. His condition was complicated by methamphetamine exposure and a viral infection, resulting in multiorgan dysfunction. Due to late diagnosis and rapid disease progression, he was ineligible for copper-histidine treatment, which could have improved outcomes. Despite supportive care, his prognosis remained poor, and he died 30 days after admission. This case underscores the importance of early detection and treatment with copper injections, as Menkes disease can mimic signs of nonaccidental trauma. Molecular genetic testing is recommended for diagnosis, particularly in cases with developmental delay, poor growth, and a family history of early deaths.
November 2019 in “Harper's Textbook of Pediatric Dermatology” Understanding normal hair growth and loss in children is key to diagnosing and treating hair disorders.
2 citations
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January 1987 in “Acta Agriculturae Scandinavica” Certain chelators lighten mink skin and hair, increase skin elasticity, and disrupt hair growth without affecting fur quality.