research Corticotropin releasing hormone and the skin 137 citations , January 2006 in “Frontiers in bioscience” CRH in the skin acts like the body's stress response system, affecting cell behavior and immune activity.
research New effects of caffeine on corticotropin‐releasing hormone (CRH)‐induced stress along the intrafollicular classical hypothalamic–pituitary–adrenal (HPA) axis (CRH‐R1/2, IP3‐R, ACTH, MC‐R2) and the neurogenic non‐HPA axis (substance P, p75NTRand TrkA) inex vivohuman male androgenetic scalp hair follicles 12 citations , April 2020 in “British Journal of Dermatology” Caffeine may help reduce stress-induced hair loss.
research Increased CRHR1 expression on monocytes from patients with AA enables a pro‐inflammatory response to corticotrophin‐releasing hormone 3 citations , October 2024 in “Experimental Dermatology” Higher CRHR1 levels in AA patients lead to increased inflammation.
research Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells April 2024 in “iScience” Ganoderma lucidum extract may help treat stress-related hair loss.
research Corticotropin-releasing hormone: An autocrine hormone that promotes lipogenesis in human sebocytes 284 citations , May 2002 in “Proceedings of the National Academy of Sciences” CRH promotes fat production in skin cells, affecting conditions like acne.