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GlossaryCentral Centrifugal Cicatricial Alopecia (CSCC)

scarring hair loss starting at the scalp's crown, common in African American women

Central Centrifugal Cicatricial Alopecia (CCCA) is a type of scarring hair loss that typically starts at the crown of the scalp and spreads outward in a circular pattern. It is most commonly seen in African American women and can lead to permanent hair loss due to the destruction of hair follicles and subsequent scarring.

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research Increased Risk of Local Recurrence in Cutaneous Squamous Cell Carcinoma Arising in Sun-Exposed Skin: A Retrospective Cohort Study

October 2023 in “Cancers”

Skin cancer in sun-exposed areas is more likely to come back.

research Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis

6 citations , December 2019 in “Frontiers in genetics”

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

research Invasive Cutaneous Squamous Cell Carcinoma of Scalp: A Case Report

2 citations , September 2022 in “Annals of Medicine and Surgery”

A man with a rare scalp cancer was successfully treated, highlighting the need for early management to prevent spread and complications.

research Roles of the Hedgehog Signaling Pathway in Cutaneous Physiology and Oncology

June 2019 in “International journal of dermatology and venereology”

The Hedgehog Signaling Pathway is important for skin and hair development and skin cancer treatment, but more research is needed to understand it fully.

research LSD1 Is Critical for Epidermal Development and Skin Barrier Formation

April 2023 in “Journal of Investigative Dermatology”

LSD1 is essential for healthy skin development and creating the skin's protective barrier.

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