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research Cytochrome P450: A Target for Drug Development for Skin Diseases

115 citations , August 2004 in “The journal of investigative dermatology/Journal of investigative dermatology”

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

research S100A8 induces cyclophosphamide-induced alopecia via NCF2/NOX2-mediated ferroptosis

2 citations , February 2025 in “Free Radical Biology and Medicine”

Blocking S100A8 can reduce chemotherapy-induced hair loss.

Antiandrogens and Androgen Inhibitors in Dermatologic Treatments

research Antiandrogens and Androgen Inhibitors

November 2020 in “Elsevier eBooks”

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

research Evaluation of dermatologic adverse events associated with aromatase inhibitors: insights from the FAERS database

2 citations , May 2025 in “Frontiers in Pharmacology”

Aromatase inhibitors can cause skin issues, especially with anastrozole and exemestane, so monitoring is important.

research Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases

51 citations , May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

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community Oral Minoxidil and Grapefruit Juice

in Research/Science 96 upvotes 3 years ago

The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

community 7 months - 7 months oral dutasteride 0.5mg, 5 months oral minoxidil 12.5mg - 34 year old male

in Progress Pictures 82 upvotes 3 years ago

Hair loss progress and treatments, specifically oral dutasteride and oral minoxidil.

community 2.5 years 1mg finasteride daily

in Progress Pictures 4882 upvotes 6 months ago

Significant hair regrowth was achieved after 2.5 years of taking 1 mg finasteride daily, without using minoxidil or microneedling. Minor side effects included a slightly thinner beard and longer time to finish during sex.

community 11 month progress on a cocktail regiment

in Progress Pictures 442 upvotes 2 years ago

The user "Dismal_Library_2264" shared their 11-month progress on a hair loss treatment regimen. They used dutasteride, topical minoxidil, dermarolling, a hair serum, and specific shampoos. They experienced some side effects but were overall satisfied with the results.

community Two years on dutasteride and minoxidil

in Progress Pictures 295 upvotes 1 year ago

The conversation discusses a user's two-year experience using oral dutasteride and minoxidil for hair loss, noting initial gains and stabilization over time, with some concerns about shedding and a weak spot at the crown. The user also mentions using testosterone cypionate and reports no significant side effects, except possibly dry eyes.

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