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Association of Rs231775 Genetic Variant of Cytotoxic T-Lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case-Control Study

research Association of Rs231775 Genetic Variant of Cytotoxic T-lymphocyte Associated Protein 4 with Alopecia Areata Disease in Males: A Case–Control Study

7 citations , July 2020 in “Immunological Investigations”

The rs231775 genetic variant is linked to a higher risk and severity of Alopecia Areata in males.

research Psoriasis is characterized by deficient negative immune regulation compared to transient delayed-type hypersensitivity reactions

15 citations , June 2015 in “F1000Research”

Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.

The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region and Hair Bulb Area in Chronic Alopecia Areata Patients

research The Contributory Roles of Th17 Lymphocyte and Cytotoxic T Lymphocyte at the Hair Bulge Region as Well as the Hair Bulb Area in the Chronic Alopecia Areata Patients

18 citations , January 2017 in “Annals of dermatology/Annals of Dermatology”

Certain immune cells contribute to severe hair loss in chronic alopecia areata, with Th17 cells possibly having a bigger impact than cytotoxic T cells.

research Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata

106 citations , January 2013 in “Clinical and Developmental Immunology”

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

research Identification of drug-specific public TCR driving severe cutaneous adverse reactions

88 citations , August 2019 in “Nature communications”

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

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