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GlossaryDasatinib

medication used to treat certain types of leukemia

Dasatinib is a medication primarily used to treat certain types of leukemia, a cancer of the blood cells. It works by inhibiting specific proteins that promote the growth of cancer cells, thereby slowing or stopping their proliferation. For professionals, it's known as a tyrosine kinase inhibitor and is effective against chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL) with the Philadelphia chromosome.

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Research

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research Dasatinib-Induced Leukotrichia in a Patient With Chronic Myelogenous Leukemia

9 citations , May 2013 in “JAMA Dermatology”

A woman's hair turned white after taking a cancer drug called dasatinib.

research Tyrosine Kinase Inhibitors – A Review on Pharmacology, Metabolism and Side Effects

508 citations , June 2009 in “Current drug metabolism”

Tyrosine kinase inhibitors effectively treat cancers but often cause skin and other side effects.

research Unique Cutaneous Reaction to Second- and Third-Generation Tyrosine Kinase Inhibitors for Chronic Myeloid Leukemia

32 citations , September 2015 in “Dermatology”

Certain leukemia drugs can cause severe skin reactions that may require stopping treatment.

research Flexural Agminated Eruptive Nevi in Langerhans Cell Histiocytosis

9 citations , May 2013 in “JAMA Dermatology”

Sunlight exposure improved a patient's skin condition, and there may be a link between a certain disease and skin growths; a leukemia treatment caused changes in hair color and growth.