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research Dental Manifestations in Vitamin D Dependent Rickets Type II with Alopecia: A Short Pictorial Case Report

July 2025 in “SVU-International Journal of Medical Sciences”

Vitamin D-dependent rickets type II (VDDR-II) is a rare genetic disorder marked by resistance to vitamin D and severe cases of alopecia. This case report highlights a child's dental issues associated with VDDR-II, including sparse, hypoplastic teeth, profound dentin involvement, and delayed teething. Current treatments focusing on phosphorus and calcium supplementation may not adequately address dental abnormalities. A comprehensive, multidisciplinary management approach involving various specialists is essential for managing this complex condition in pediatric patients.

research Nuclear Factor I-C Promotes Proliferation and Differentiation of Apical Papilla-Derived Human Stem Cells In Vitro

24 citations , February 2015 in “Experimental Cell Research”

NFIC helps human dental stem cells grow and become tooth-like cells.

research From Structural Resilience to Cell Specification: Intermediate Filaments as Regulators of Cell Fate

9 citations , November 2020 in “The FASEB journal”

Intermediate filaments are crucial for cell differentiation and stem cell function.

research TGF-β Family Signaling in Epithelial Differentiation and Epithelial-Mesenchymal Transition

82 citations , February 2017 in “Cold Spring Harbor Perspectives in Biology”

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

research The Role of Thymosin Beta 4 on Odontogenic Differentiation in Human Dental Pulp Cells

37 citations , April 2013 in “PLoS ONE”

Thymosin Beta 4 helps human dental pulp cells develop into tooth-forming cells, suggesting it could aid dental regeneration.

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Community Join

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community Found this meme on a forum……..

in Satire 150 upvotes 2 years ago

The conversation is about a meme related to hair loss that influenced someone to start taking finasteride. Another person agrees that the meme accurately represents the situation.

community 4 month update: daily min and topical fin micro needling Progress Pictures

in Progress Pictures 434 upvotes 2 years ago

User shares 4-month progress using daily minoxidil, topical finasteride, and microneedling. Results spark debate on effectiveness and authenticity.

community Why is human evolution like this 😂

in Chat 3 years ago

Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

community Oral dutasteride vs topical efficacy

in Finasteride/Dutasteride 60 upvotes 1 year ago

The user switched from topical minoxidil/dutasteride to oral dutasteride, resulting in hair loss. They resumed topical treatment without regrowth and are considering switching to finasteride due to poor results with oral dutasteride.

community Yes your lifestyle and diet has its role in hair loss.

in Chat 296 upvotes 6 months ago

Diet and lifestyle changes can reduce hair shedding but won't regrow hair lost to genetic male pattern baldness. Treatments like finasteride and dutasteride are necessary for significant hair regrowth.

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