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research Cardiovascular risks and elevation of serum DHT vary by route of testosterone administration: a systematic review and meta-analysis

122 citations , November 2014 in “BMC Medicine”

Oral testosterone therapy raises heart risk more than other methods.

The Dihydrotestosterone Hypothesis of Prostate Cancer and Its Therapeutic Implications

research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications

57 citations , January 1986 in “The Prostate”

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido

research A Randomized Trial of Oral DHEA Treatment for Sexual Function, Well-Being, and Menopausal Symptoms in Postmenopausal Women with Low Libido

48 citations , July 2009 in “The Journal of Sexual Medicine”

DHEA did not improve sexual function, well-being, or menopausal symptoms in postmenopausal women with low libido but caused side effects like acne and increased facial hair.

research The safety of 52 weeks of oral DHEA therapy for postmenopausal women

46 citations , May 2009 in “Maturitas”

Taking DHEA for a year is generally safe for postmenopausal women but may cause acne and more facial hair without improving metabolism or aging.

research Morphology of the testis and the epididymis in rats with dihydrotestosterone (DHT) deficiency.

34 citations , January 2004 in “PubMed”

DHT deficiency in rats reduces sperm content and affects testis structure over time.

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community Is DHT actually the cause of male pattern hair loss or just a correlating factor? Why I think the research is more complicated than we're told and why I've been looking into GHK-Cu

in Research/Science 78 upvotes 2 months ago

DHT is not the only cause of male pattern hair loss; genetic sensitivity, inflammation, and fibrosis also contribute. GHK-Cu, a copper peptide, is being explored as an alternative treatment to finasteride and minoxidil, showing potential in improving follicle health.

community DHT is NOT very important for adults, is it?

in Finasteride/Dutasteride 118 upvotes 3 months ago

A user experienced negative side effects, including low libido and lack of motivation, after using finasteride for hair loss and felt better after stopping it. Others shared similar experiences with finasteride and dutasteride, while some reported no side effects, showing varied individual responses.

community DHI 3k grafts front. Photo order: -1 month, 2 weeks, 1 month, 2 months

in Transplants 5 upvotes 3 months ago

The user underwent a DHI hair transplant with 3,066 grafts at Hairtec in the Netherlands and is using finasteride and minoxidil to restore hair, particularly at the crown. They plan to adjust minoxidil dosage and consult with a dermatologist in September.

community DHT nearly doubled after switching to oral Fin

in Chat 4 upvotes 4 months ago

The user switched from topical Minoxidil and Finasteride to oral Finasteride and reduced testosterone, expecting to lower DHT, but instead, DHT increased and hair loss worsened. The user is seeking advice on whether to return to the previous topical treatment or if others have experienced similar issues with oral Finasteride while on TRT.

community DHT Isn’t the Only Factor in Hair Loss and That Might Be the Key to a Real Cure

in Research/Science 370 upvotes 5 months ago

Hair loss involves more than just DHT, with genetic factors like TRPS affecting hair follicles. Treatments such as Amplifica's AMP-601 and AMP-303 target stem cells for potential hair growth solutions.

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