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GlossaryDifferentially Expressed Proteins

proteins with varying expression levels between different biological conditions

Differentially Expressed Proteins (DEPs) are proteins that show significant differences in their levels of expression between two or more biological conditions, such as healthy versus diseased tissue. Identifying DEPs can help researchers understand the molecular mechanisms underlying various conditions, including alopecia, by highlighting which proteins are upregulated or downregulated in response to specific factors.

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research Combination of Transcriptomics and Proteomics Reveals Differentially Expressed Genes and Proteins in the Skin of EDAR Gene-Targeted and Wildtype Cashmere Goats

1 citations , April 2023 in “Animals”

Deleting the EDAR gene in Cashmere goats affects genes and proteins related to hair growth.

Proteomics-Based Screening of Differentially Expressed Proteins in Skin of Chinese Merino Fine Sheep (JunKen Type) by Gender

research [Proteomics-based screening of differentially expressed proteins in skin of Chinese merino fine sheep (JunKen type) of different gender].

1 citations , October 2022 in “PubMed”

Gender affects wool traits in sheep, with males and females showing differences in skin proteins related to wool growth.

Proteomic Analysis Identifies Differentially Expressed Proteins Participating in Forming Type III Brush Hair in Yangtze River Delta White Goat

research Proteomic analysis identifies differentially expressed proteins participating in forming Type III brush hair in Yangtze River Delta white goat

8 citations , January 2015 in “Genetics and molecular research”

Researchers found four key proteins that affect the development of a specific hair type in Yangtze River Delta white goats.

Discovery of Differentially Expressed Genes in Cashmere Goat Hair Follicles by RNA Sequencing

research Discovery of differentially expressed genes in cashmere goat (Capra hircus) hair follicles by RNA sequencing

5 citations , January 2016 in “Genetics and Molecular Research”

Researchers found 617 genes that behave differently in cashmere goat hair follicles, which could help understand hair growth.

research Exploring Differentially Expressed Genes by RNA-Seq in Cashmere Goat (Capra hircus) Skin during Hair Follicle Development and Cycling

61 citations , April 2013 in “PloS one”

The study found key genes and pathways involved in cashmere goat hair growth stages.

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community New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase

in Research/Science 124 upvotes 2 years ago

Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 1 year ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

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