15 citations
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July 2004 in “Journal of morphology”
Monotreme hairstructure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.
A permanent hair loss solution could involve reprogramming hair follicles to resist DHT using mRNA and siRNA. However, high costs, safety concerns, and the pharmaceutical industry's preference for ongoing treatments over one-time cures are major obstacles, with finasteride and minoxidil remaining standard treatments.
28-year-old struggles with aggressive hair loss since 18, used minoxidil with limited success. Tried hair systems but found them expensive, shaved head for job interviews but plans to return to hair systems.
Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.
PP405 (Everychem 3HP) may help with hair regrowth, with mixed user experiences. Users often combine it with minoxidil and finasteride, but there are concerns about its efficacy and side effects.
A user shared their 3.5-year hair loss treatment journey using finasteride and minoxidil, showing significant hair density improvement and no noticeable side effects. The user also mentioned the confidence boost from shaving their head and the positive impact of the treatments.