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GlossaryDisulfide Bonds

strong covalent links between sulfur atoms in proteins

Disulfide bonds, also known as S-S bonds, are strong covalent bonds formed between two sulfur atoms, typically within the amino acid cysteine. These bonds play a crucial role in stabilizing the three-dimensional structure of proteins, including keratin in hair, by linking different parts of the protein chain. In hair, disulfide bonds contribute to its strength and elasticity, and their alteration can affect hair texture and resilience.

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research The role of disulfide bond formation in the structural transition observed in the intermediate filaments of developing hair

39 citations , June 2012 in “Journal of Structural Biology”

Disulfide bonds are crucial for hair structure during keratinization.

research The susceptibility of disulfide bonds to modification in keratin fibers undergoing tensile stress

11 citations , April 2022 in “Biophysical Journal”

Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.

research Effect of Disulfide Bonds in Human Hair Fibers on the Melting Behavior of Their Crystalline Structure

1 citations , January 2009 in “Journal of S C C J”

Changing disulfide bonds in human hair affects its melting behavior and thermal stability.

research Effect of disulfide bonds in human hair fibers on the melting behavior of their crystalline structure

March 2010 in “International Journal of Cosmetic Science”

Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.