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Exhaustive Analysis of Scalp Hair Regression: Subjective and Objective Perception from Initial Hair Loss to Severe Miniaturization and Drug-Induced Regrowth

research Exhaustive analysis of scalp hair regression: subjective and objective perception from initial hair loss to severe miniaturisation and drug-induced regrowth

3 citations , January 2021 in “Plastic and Aesthetic Research”

Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.

research Anatomy and Biology of Hair at Different Ages

1 citations , December 2023

Hair grows in cycles and changes with age, starting from fetal development.

research Hair removal with intense pulsed light

45 citations , June 2004 in “Lasers in Medical Science”

Intense pulsed light (IPL) is an efficient and safe method for hair removal, reducing hair by about 80%.

research Dormant tumor cells in ret transgenic mouse melanoma model and their interaction with memory T cells

January 2012 in “heiDOK (Heidelberg University)”

Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.

The Effect of Plasma Rich in Growth Factors Combined with Follicular Unit Extraction Surgery for the Treatment of Hair Loss: A Pilot Study

research The effect of plasma rich in growth factors combined with follicular unit extraction surgery for the treatment of hair loss: A pilot study

12 citations , October 2017 in “Journal of Cosmetic Dermatology”

Combining plasma rich in growth factors with hair transplant surgery may lead to faster recovery and better outcomes for hair loss treatment.

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community Confused why people are calling PP405 a cure...it never claimed to be able to undo miniaturization or revert vellus back to terminal hairs. It seems to be more of a growth stimulant like minoxidil.

in Research/Science 55 upvotes 1 year ago

PP405 is not a cure for hair loss but may reactivate dormant hair follicles, similar to minoxidil. It is unlikely to help with miniaturized or vellus hairs and is still in trial phases, with availability expected around 2030.

community Found a slide summary for PP405

in Research/Science 33 upvotes 4 months ago

PP405 shows promise in stimulating new terminal hair growth by activating dormant follicles, with no systemic adverse effects observed in a short-term trial. However, long-term efficacy remains unproven, and further trials are needed to confirm its potential as a hair loss treatment.

community Haircafe slams pp405 presentation. Are results really that bad?

in Treatment 65 upvotes 4 months ago

PP405 shows promise in activating dormant hair follicles and increasing hair counts but lacks detailed efficacy data compared to minoxidil and finasteride. Opinions are mixed, with some optimism and skepticism about its effectiveness.

community Welp - pp405 conference showed nothing

in Update 77 upvotes 4 months ago

PP405 shows potential for hair growth by increasing terminal hair and converting vellus hairs, but results are modest and more waiting is needed. It complements existing treatments like minoxidil and finasteride, but won't replace them.

community A Short Recap on PP405 and AAD 2026

in Update 4 months ago

PP405 is a promising experimental topical treatment for alopecia that reactivates dormant hair follicles by targeting cellular energy, with large-scale trials planned for 2026. While it shows potential, it cannot regenerate permanently destroyed follicles, making hair transplants the only guaranteed solution for advanced baldness currently.

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learn Thymosin Beta 4

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