February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This theoretical paper suggests a novel gut-centric cause for a subset of Post-Finasteride Syndrome (PFS) cases, which are not fully explained by androgen deprivation. It hypothesizes that a chronic overgrowth of hydrogen sulphide (H₂S)-producing bacteria in the small intestine acts as a systemic mitochondrial toxin. This condition may create a dysbiotic feedback loop that perpetuates the epigenetic silencing initially triggered by finasteride exposure. The paper proposes that this acquired metabolic dysfunction, driven by gut-derived toxins, could explain the persistence of PFS symptoms and highlights the small intestinal microbiome as a potential therapeutic target.
February 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This theoretical paper suggests a novel gut-centric cause for a subset of Post-Finasteride Syndrome (PFS) cases, which are not fully explained by androgen deprivation. It hypothesizes that a chronic overgrowth of hydrogen sulphide (H₂S)-producing bacteria in the small intestine acts as a systemic mitochondrial toxin. This condition may create a dysbiotic feedback loop that perpetuates the epigenetic silencing initially triggered by finasteride exposure. The paper proposes that this acquired metabolic dysfunction, driven by gut-derived toxins, could explain the persistence of PFS symptoms and highlights the small intestinal microbiome as a potential therapeutic target.
September 2025 in “Cosmoderma” Pandemic stress worsens hair loss and skin issues, suggesting combined mental and skin care treatments.
February 2026 in “International Journal of Web of Multidisciplinary Studies” Restoring microbial balance and using exosome therapies may help treat hair disorders like alopecia and acne.
3 citations
,
September 2023 in “Frontiers in immunology” Chronic inflammatory skin diseases are caused by disrupted interactions between skin cells and immune cells.