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WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

research WNT10A Mutations Are a Frequent Cause of a Broad Spectrum of Ectodermal Dysplasias with Sex-Biased Manifestation Pattern in Heterozygotes

197 citations , June 2009 in “American journal of human genetics”

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

research Uncombable Hair Syndrome: Observations on Response to Biotin and Occurrence in Siblings with Ectodermal Dysplasia

101 citations , July 1985 in “Journal of the American Academy of Dermatology”

Biotin improved hair growth and combability in one child with uncombable hair syndrome.

WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

research WNT10A Mutation Causes Ectodermal Dysplasia by Impairing Progenitor Cell Proliferation and KLF4-Mediated Differentiation

96 citations , June 2017 in “Nature Communications”

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

research A Mutation in the Hair Matrix and Cuticle Keratin KRTHB5 Gene Causes Ectodermal Dysplasia of Hair and Nail Type

60 citations , March 2006 in “Journal of Medical Genetics”

A mutation in the KRTHB5 gene causes hair and nail issues.

research Epidermal Dysplasia and Abnormal Hair Follicles in Transgenic Mice Overexpressing Homeobox Gene MSX-2

49 citations , August 1999 in “Journal of Investigative Dermatology”

Overexpressing the MSX-2 gene in mice causes skin and hair growth issues.

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Community Join

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community Anyone lose hair on selenium sulfide? (Selsun Blue)

in Treatment 2 months ago

Selenium sulfide shampoo helped with a sore scalp but may cause hair root damage. Users experienced hair loss with selenium sulfide and ketoconazole, suggesting reducing use if hair loss occurs.

community Hair loss research is a money grab

in Chat 217 upvotes 1 month ago

Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

community What is going on with my scalp?

in Female 23 upvotes 2 years ago

A user named Mmherak is experiencing hair loss, with low B12 and iron deficiency, and has been recommended minoxidil and spironolactone by dermatologists. Other users suggest seborrheic dermatitis or dandruff, recommending treatments like Nizoral shampoo, ketoconazole, and Selsun Blue.