Search

for
Search:

Learn

0 / 0 results

— no results

Research

5 / 954 results

research The Function of LPR1 Is Controlled by an Element in the Promoter and Is Independent of SUMO E3 Ligase SIZ1 in Response to Low Phosphate Stress in Arabidopsis thaliana

49 citations , January 2010 in “Plant and Cell Physiology”

LPR1 regulates root growth under low phosphate stress independently of SIZ1 in Arabidopsis thaliana.

research Xinyang Tablet Ameliorates Sepsis-Induced Myocardial Dysfunction by Regulating Beclin-1 to Mediate Macrophage Autophagy and M2 Polarization Through LncSICRNT1 Targeting E3 Ubiquitin Ligase TRAF6

6 citations , November 2023 in “Chinese Medicine”

Xinyang Tablet improves heart function in sepsis by reducing inflammation.

research Smad7-Induced Beta-Catenin Degradation Alters Epidermal Appendage Development

147 citations , September 2006 in “Developmental Cell”

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

research Comparative Ubiquitinomics of Human Skin Reveals Insulin Receptor Ubiquitination as a Regulator of Collagen Secretion

December 2025

Ubiquitination of the insulin receptor regulates collagen secretion in human skin.

research The Role of R-Spondins and Their Receptors in Bone Metabolism

25 citations , May 2016 in “Progress in Biophysics & Molecular Biology”

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

View more "e3 ligase" in research →

Community Join

5 / 18 results

community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

in Research/Science 136 upvotes 1 year ago

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Peptides that Stop Hair Loss? | In-depth Literature Review Video

in Research/Science 74 upvotes 1 year ago

Peptides like TB500, KPV, GHK-CU, and BPC-157 are overhyped for hair growth with limited proven effectiveness in humans. Combining peptides with delivery methods like iontophoresis and sonophoresis shows promise, but many claims remain unproven.

community hair loss treatment alternatives and ideas to improve gain

in Treatment 3 upvotes 2 years ago

The post discusses using finasteride, minoxidil, ketoconazole, and a dermaroller for hair loss, along with spearmint capsules, pueraria mirifica, saw palmetto, biotin, and vitamins. The user is also considering microdosing finasteride with trans treatment and mentions the potential of herbal enemas and hair systems.

community How many mgs of zinc should I take while taking fin? I want to potentially offset side effects but not ruin the effectiveness of fin. I take .5 mg fin daily

in Chat 13 upvotes 4 years ago

A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.

View more "e3 ligase" in community →