learn Alopecia Areata
autoimmune disorder causing patchy hair loss
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5 / 801 resultslearn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Finasteride
Frontline, gold standard treatment for combatting androgenic alopecia
learn Tofacitinib
a JAK inhibitor for alopecia areata and other autoimmune conditions
learn Valproic acid
an anticonvulsant repurposed for hair loss via histone inhibition
Research
5 / 1000+ resultsresearch Obesity and Low-Grade Inflammation among Young Finnish Men with Early-Onset Alopecia
Young Finnish men with more severe hair loss may have higher inflammation and obesity, increasing future heart disease risk.
research Clinical Characteristics and Prognostic Factors in Early-Onset Alopecia Totalis and Alopecia Universalis
Early-onset alopecia, especially with a family history, leads to worse outcomes and more related health issues.
research Prevalence of Metabolic Syndrome and Cardiovascular Risk Factors in Early Onset Male Androgenetic Alopecia - A Cross Sectional Study in a Tertiary Care Hospital
Early-onset male hair loss may be linked to higher cardiovascular risk.
research Association of Early-onset Androgenetic Alopecia and Metabolic Syndrome
Early-onset hair loss in young males is linked to a higher risk of metabolic syndrome.
research Impaired metabolic effects of metformin in men with early-onset androgenic alopecia
Metformin is less effective in men with early-onset hair loss.
Community Join
5 / 1000+ resultscommunity Efficacy and Tolerability of N-Acetyl-Cysteine for Treatment of The Early-onset Androgenetic Alopecia in Men
N-Acetyl-Cysteine (NAC) was found to improve hair parameters in men with early-onset androgenetic alopecia, showing increased terminal hair count and decreased vellus hair count, with good tolerability. NAC, used alone or with minoxidil, may help due to its antioxidant properties, though its effectiveness can vary among individuals.
community Is it possible for androgenic alopecia to begin at early adolescent years?
Hair loss can begin in early adolescence and cause mental anguish. Treatments mentioned include eating cruciferous vegetables, engaging in physical activity, and maintaining scalp hygiene.
community 19 years old - 3 months of min+fin
A 19-year-old has been using a regimen of 5% topical minoxidil and 1mg oral finasteride for three months to combat early-onset balding. The user reports some progress and plans to continue the current treatment, while others suggest considering additional treatments like dutasteride for more aggressive cases.
community My Theory Of Androgenic Alopecia
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.
community PP405 Phase 2a press release with early results
PP405 shows promise in hair regrowth, with 31% of participants experiencing over 20% increase in hair density after 8 weeks. Phase 3 trials are expected in 2026, with potential market availability by 2029-2031.