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Embryo-Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903, a Novel Potassium-Competitive Acid Blocker, in Pregnant Rats

research Embryo‐Fetal Developmental Toxicity and Toxicokinetics Studies of YWS1903, a Novel Potassium‐Competitive Acid Blocker, in Pregnant Rats

May 2025 in “Birth Defects Research”

YWS1903 is safe for pregnant rats at moderate doses but causes fetal issues at high doses.

research Part 1. Genetic pathway of maternal transmission in Topiramate-treated zebrafish modelPart 2.Effects of herbal medicine on zebrafish embryos

January 2019 in “Spectrum Research Repository (Concordia University)”

Topiramate impairs gene transmission in zebrafish, while Ginkgo biloba reduces harmful effects of high β-catenin levels.

research Lymphotoxin-β regulates periderm differentiation during embryonic skin development

12 citations , August 2007 in “Human Molecular Genetics”

Lymphotoxin-β is crucial for proper skin development in embryos.

research Sperm aneuploidy in infertile male patients: a systematic review of the literature

26 citations , October 2014 in “Andrologia”

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

research Recurrent implantation failure: A comprehensive summary from etiology to treatment

128 citations , January 2023 in “Frontiers in Endocrinology”

Individualized treatment and support can help most couples with recurrent implantation failure achieve pregnancy.

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community IVF process on Finasteride and effects of stopping finasteride.

in Finasteride/Dutasteride 135 upvotes 8 months ago

Concerns about finasteride affecting sperm quality and embryo abnormalities during IVF. The user plans to stop finasteride for 6 months and use minoxidil, microneedling, a red light cap, and saw palmetto shampoo to manage hair loss.

community Male (24) Using Dutasteride Since 2020 – Concerns About Having Kids

in Finasteride/Dutasteride 90 upvotes 1 year ago

A 24-year-old male using dutasteride for hair loss is worried about its effects on fertility and future children's health. Users advise consulting a doctor, possibly switching to finasteride, or stopping dutasteride before conception due to its impact on sperm count.

community Reminder: You cannot donate blood if you are taking Fin or Dut

in Finasteride/Dutasteride 729 upvotes 1 year ago

You cannot donate blood if you are taking finasteride or dutasteride due to potential risks to pregnant women. Finasteride has a shorter wait time to donate blood compared to dutasteride, and both oral and topical forms can disqualify you from donating.

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