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research LC-ESI-QTOF-MS/MS Analysis, Cytotoxic, Antiviral, Antioxidant, and Enzyme Inhibitory Properties of Four Extracts of Geranium pyrenaicum Burm. f.: A Good Gift from the Natural Treasure

53 citations , July 2021 in “International Journal of Molecular Sciences”

Geranium pyrenaicum extracts show potential for cancer, antiviral, and enzyme inhibition treatments.

research Phenolic composition, enzyme inhibitory, and antioxidant activity of Bituminaria bituminosa

6 citations , October 2016 in “Food Science and Biotechnology”

The water extract of Bituminaria bituminosa, high in phenolic compounds, shows strong antioxidant and enzyme inhibitory potential.

A Peptide Derivative with Known Anti-Wrinkle Properties Identified as Potent Dipeptidylpeptidase-4 Inhibitor

research 557 A peptide derivative with known anti-wrinkle properties was identified as potent dipeptiylpeptidase-4 inhibitor

April 2016 in “Journal of Investigative Dermatology”

A peptide known for reducing wrinkles also effectively inhibits an enzyme linked to skin inflammation and acne.

research Effect of procyandin oligomers on oxidative hair damage

10 citations , January 2011 in “Skin research and technology”

Procyanidin oligomers can protect hair from oxidative damage and could be good for hair care products.

research Human epidermal transglutaminase. Preparation and properties.

138 citations , December 1976 in “Journal of Biological Chemistry”

The enzyme from human skin can cross-link proteins and needs calcium to work.

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Community Join

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community Is there a topical androgen receptor blocker so we don't have to fuck with the enzyme and destroy our allopregnanolone, but go and hit the end target straight?

in Treatment 44 upvotes 2 years ago

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

community Quit vaping/smoking = 80% less loss

in Research/Science 235 upvotes 2 years ago

Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

community Stop Using Salicylic acid on your face if using minoxidil for beard growth

in Product 20 upvotes 2 years ago

Salicylic acid can reduce the effectiveness of minoxidil for beard growth. Users discuss avoiding salicylic acid when using minoxidil.

community By how much percent does nizoral 2% shampoo reduces scalp dht?

in Ketoconazole 7 upvotes 1 year ago

Ketoconazole shampoo may reduce scalp DHT by around 10% but is not effective enough to stop hair loss on its own. For better results, finasteride, minoxidil, and lifestyle changes are recommended.

community Better Than Minoxidil? Topical Sodium Valproate

in Research/Science 53 upvotes 1 year ago

Topical sodium valproate may promote hair growth by inhibiting GSK3β, allowing beta-catenin to proliferate, but it has potential side effects and requires more research. The conversation also mentions skepticism about a product called Vdphlo1, which includes sodium valproate and other ingredients.

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Learn

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learn Neem Oil

natural substance from Neem tree with medicinal and pesticidal properties

learn Saw Palmetto

a natural and far less effective alternative to Finasteride

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Overview

learn Baricitinib

JAK inhibitor that reduces inflammation and immune attacks on hair follicles, leading to potential hair regrowth, especially in alopecia areata cases

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